Ductal Carcinoma In Situ (DCIS): the Importance of Patient-Reported Outcomes (PRO)

AbstractPurpose of ReviewPatient reported outcomes (PROs) are an optimal method for assessing quality of life (QOL), including physical and psychosocial health. This review summarizes PROs frequently assessed in the setting of a DCIS diagnosis.Recent FindingsHealth-related QOL has generally been found to be modestly affected in women with DCIS and similar to women with invasive breast cancer. Several studies reported a substantial negative impact on sexual health and body image, including some differences based on surgery type. Some patients experience pain after treatment, although many physical symptoms resolve. The prevalence of anxiety and depression varied based on assessment timing, with symptoms improving overtime. Women with DCIS often overestimate the risks associated both with DCIS and invasive cancer.SummaryPROs provide critical information regarding the experiences of women following a DCIS diagnosis. Continued inclusion of PROs in clinical trials is warranted, further informing treatment decisions and adequately preparing patients for what to expect following treatment.
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research