Ginsenoside 20(S)-Rg3 upregulates HIF-1 α-targeting miR-519a-5p to inhibit the Warburg effect in ovarian cancer cells.

In conclusion, 20(S)-Rg3 upregulates miR-519a-5p via reducing DNMT3A-mediated DNA methylation to inhibit HIF-1α-stimulated Warburg effect in ovarian cancer. PMID: 32271958 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32271958?dopt=Abstract

Source: Clinical and Experimental Pharmacology and Physiology - April 8, 2020 Category: Drugs & Pharmacology Authors: Lu J, Chen H, He F, You Y, Feng Z, Chen W, Li X, Zhao L Tags: Clin Exp Pharmacol Physiol Source Type: research