Ocular Findings Associated with Hypoparathyroidism.

Conclusion: We determined thinner CCT and RNFL values in patients with hypoparathyroidism related to serum calcium levels together with a significant deepness in ACD. PMID: 32267183 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Related Links:

Authors: Cui Y, Li Y, Ning J, Mi Y, Wang X, Qiu Z, Li L, Gou X Abstract Mechanical allodynia, which develops in patients of diabetes mellitus as a neuropathic manifestation, remains without an effective treatment. The aim of the present study was to investigate the effects and potential mechanisms underlying resveratrol (RES) in a rat model of streptozocin (STZ)‑induced diabetic mechanical allodynia (DMA). The rat model of DMA was established by the administration of an intraperitoneal injection of STZ. From day 8 post‑STZ injection, rats were administered with an intragastric injection of various doses of RES ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Publication date: Available online 29 May 2020Source: The Journal of Foot and Ankle SurgeryAuthor(s): Kamil M. Amer, Jennifer E. Thomson, Rami Amer, Arsalaan Choudhry, Aisha Chaudhry, Iftikhar Chaudhry
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
About 50 million of the U.S. adult population suffer from chronic pain. It is a complex disease in its own right for which currently available analgesics have been deemed woefully inadequate since ~20% of the sufferers derive no benefit. Vitamin D, known for its role in calcium homeostasis and bone metabolism, is thought to be of clinical benefit in treating chronic pain without the side-effects of currently available analgesics. A strong correlation between hypovitaminosis D and incidence of bone pain is known. However, the potential underlying mechanisms by which vitamin D might exert its analgesic effects are poorly und...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conditions:   Acute Respiratory Distress Syndrome;   COVID-19 Intervention:   Procedure: Stellate Ganglion Block Sponsor:   West Virginia University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somati...
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Research Source Type: research
This study shows the expression of GRM1-8 mRNAs in rat and human adrenal glands and indicates that glutamate, through the activation of mGluRs, may play various physiological roles in the adrenal gland. Furthermore, mGluR1 may be involved in catecholamine biosynthesis by regulating TH, and mGluR5 may affect cortical and medullar hormone levels by regulating microvascular function.
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Cell Death &Disease, Published online: 27 May 2020; doi:10.1038/s41419-020-2593-yActivation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
Source: Cell death and disease - Category: Internal Medicine Authors: Source Type: research
Condition:   Post-Dural Puncture Headache Intervention:   Drug: Sphenopalatine Ganglion Block using 4% lidocaine Sponsor:   Zagazig University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Neuronal Nogo-A in the DRG may be involved in regeneration and play a protective role in the CEC model. Whereas Nogo-A, released from the injured axons or expressed by Schwann cells, may act as an inhibiting factor in the process of CEC repairment. Thus, blocking the Nogo-A/NgR signaling pathway can alleviate mechanical allodynia by apoptosis inhibition. PMID: 32446356 [PubMed - in process]
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Tags: Biochem Biophys Res Commun Source Type: research
AbstractIntroductionNeuroimaging studies of patients with bipolar disorder (BD) have recently revealed neurodegenerative changes in the central nervous system. Optical coherence tomography (OCT) imaging of the retina, as an extension of brain, may be a biomarker in understanding the neurobiology of the disease. To assess OCT as a tool to detect neurodegeneration in BD we compared the retinal changes between patients with BD and healthy individuals.MethodsWe performed complete ophthalmological examinations and took OCT images for 70 eyes of 70 patients with BD, and for age and sex ‐matched individual controls. We compared...
Source: Asia-Pacific Psychiatry - Category: Psychiatry Authors: Tags: ORIGINAL ARTICLE Source Type: research
More News: Allergy & Immunology | Calcium | Endocrinology | Ganglions | Hormones | Opthalmology | Phosphorus | Study | Vitamin A