HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic {beta}-cells in vitro by activation of Smoothened [Research Articles]

In conclusion, the protective effect of HDL to counter ER stress and β-cell death involves the transport, generation, and mobilization of oxysterols for activation of the Hh signaling receptor SMO

Source: The Journal of Lipid Research - March 31, 2020 Category: Lipidology Authors: Yalcinkaya, M., Kerksiek, A., Gebert, K., Annema, W., Sibler, R., Radosavljevic, S., Lütjohann, D., Rohrer, L., von Eckardstein, A. Tags: Research Articles Source Type: research