Biological Activity of Cerium Dioxide Nanoparticles.

This article is protected by copyright. All rights reserved. PMID: 32208546 [PubMed - as supplied by publisher]
Source: Biomed Res - Category: Research Authors: Tags: J Biomed Mater Res A Source Type: research

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Authors: Arnaout A, Varela NP, Allarakhia M, Grimard L, Hey A, Lau J, Thain L, Eisen A Abstract Background: In Ontario, there is no clearly defined standard of care for staging for distant metastasis in women with newly diagnosed and biopsy-confirmed breast cancer whose clinical presentation is suggestive of early-stage disease. This guideline addresses baseline imaging investigations for women with newly diagnosed primary breast cancer who are otherwise asymptomatic for distant metastasis. Methods: The medline and embase databases were systematically searched for evidence from January 2000 to April 2019, and t...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
Conclusion: PET with 11C-vorozole is a useful technique for measuring aromatase expression in individual breast lesions, enabling noninvasive quantitative measurement of baseline and posttreatment aromatase availability in primary tumors and metastatic lesions.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Clinical Source Type: research
Medical imaging saves millions of lives each year, helping doctors detect and diagnose a wide range of diseases, from cancer and appendicitis to stroke and heart disease. Because non-invasive early disease detection saves so many lives, scientific investment continues to increase. Artifical intelligence (AI) has the potential to revolutionize the medical imaging industry by sifting through mountains of scans quickly and offering providers and patients with life-changing insights into a variety of diseases, injuries, and conditions that may be hard to detect without the supplemental technology. Images are the largest source...
Source: MDDI - Category: Medical Devices Authors: Tags: Imaging Source Type: news
Publication date: June 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 6Author(s): Natalia Roszkowski, Selina Lam, Ellen Copson, Ramsey Cutress, Rachel Oeppen
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Conclusions: This proof-of-concept study demonstrates that high-resolution FDG-PET/CT can facilitate intra-operative margin assessment during BCS. This technique achieves good sensitivity and specificity and may therefore reduce re-operation rates in the future. PMID: 32452298 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
Breast MRI can produce more false positives on initial screening in women at...Read more on AuntMinnie.comRelated Reading: Bilateral breast MRI needed even after mastectomy Who gets breast cancer treatment during a pandemic? MRI features help predict breast cancer prognosis Shorter MRI works for patients with breast cancer history Breast MRI works as presurgical toolComments: 5/28/2020 3:40:02 AMDaniel Corcos Many high-risk women carry mutations in genes involved in the repair of DNA breaks caused by X-rays. As mammography screening leads to a high cancer incidence in the general population (Corcos &Bleyer,...
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
By MICHEL ACCAD Last month marked the 400th anniversary of the birth of John Graunt, commonly regarded as the father of epidemiology.  His major published work, Natural and Political Observations Made upon the Bills of Mortality, called attention to the death statistics published weekly in London beginning in the late 16th century.  Graunt was skeptical of how causes of death were ascribed, especially in times of plagues.  Evidently, 400 years of scientific advances have done little to lessen his doubts!  A few days ago, Fox News reported that Colorado governor Jared Polis ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: COVID-19 Medical Practice Physicians Diagnosis MICHEL ACCAD Source Type: blogs
Fluorescent silica nanoparticles (SNPs) are introduced as a robust labeling strategy to visualize tumor cells within mineralized bone from in vitro and in vivo studies. SNP labeling efficiency of MDA ‐MB‐231 breast cancer cells is characterized using a broad range of bone processing and imaging techniques. SNPs are tools with the potential to increase the understanding of mineral contributions to bone metastasis. AbstractDuring breast cancer bone metastasis, tumor cells interact with bone microenvironment components including inorganic minerals. Bone mineralization is a dynamic process and varies spatiotemporally as a ...
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
CONCLUSION: Bone scans improved in 38% of patients with metastatic hormone receptor positive breast cancer and remained stable in an additional 12% for a minimum duration of 12 weeks on cabozantinib. Further investigations should assess the activity of cabozantinib in combination with other hormonal and other breast cancer therapies and determine whether bone scan responses correlate with meaningful antitumor effects. IMPLICATION FOR PRACTICE: Most patients with metastatic hormone receptor positive (HR+) breast cancer have bone involvement, and many have bone-only disease which is difficult to evaluate for resp...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
In conclusion, the combination of continuous dosing of veliparib and every-3-week carboplatin demonstrated activity and an acceptable toxicity profile. Decrease in SUVmax on 18 FLT-PET scan during the first cycle of this therapy can identify patients who are likely to have a response. IMPLICATIONS FOR PRACTICE: The BROCADE studies suggest that patients with BRCA mutation benefit from addition of the poly(ADP-ribose) polymerase inhibitor veliparib to carboplatin plus paclitaxel. This study demonstrates that a higher dose of veliparib is tolerable and active in combination with carboplatin alone. With growing interest in ima...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
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