Atorvastatin alleviates left ventricular remodeling in isoproterenol-induced chronic heart failure in rats by regulating the RhoA/Rho kinase signaling pathway.

CONCLUSION: We demonstrated that atorvastatin inhibits LVR and improves cardiac function in rats with isoproterenol-induced CHF through inhibition of the RhoA/Rho kinase signaling pathway. PMID: 32144744 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32144744?dopt=Abstract

Source: Pharmacological Reports - March 5, 2020 Category: Drugs & Pharmacology Authors: Sun D, Zhang F, Ma T, Zhang Y, Liang Z Tags: Pharmacol Rep Source Type: research