Clinical and Microbiological Diagnosis of Nonprimary Cytomegalovirus Infection in Pregnancy With Symptomatic Congenital Cytomegalovirus Infection

We report a case of nonprimary CMV infection in pregnancy with fetal neurological alterations. A positive quantitative polymerase chain reaction in amniotic fluid (AF) confirmed the diagnosis of cCMV infection that triggered a voluntary termination of pregnancy. Quantitative polymerase chain reaction assays of AF are used to confirm a fetal cCMV infection, and the invasive amniocentesis procedure is justified when abnormalities are found in ultrasound control, although they are not validated to use in AF.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research