Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China

Conditions:   Colorectal Cancer;   Adenomatous Polyps;   Adenoma;   Advanced Adenoma Interventions:   Diagnostic Test: Multitarget stool FIT-DNA test - ColoClear;   Diagnostic Test: FIT;   Procedure: Colonoscopy Sponsors:   Zhejiang University;   New Horizon Health Technology Co., Ltd;   Beijing Mingze Technology Co., Ltd. Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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CONCLUSIONS: Our findings support the protective effect a normal weight against advanced adenomas. Reduction of BMI value should be pursued in healthy programs. PMID: 32233893 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Authors: Dano H, Baldin P, Demetter P, Driessen A, Hoorens A, Sagaert X, Van Huysse J, Verset L, Jouret-Mourin A Abstract Colorectal cancer (CRC) has become the most common malignancy in our country. Routine screening colonoscopy is on the rise. With the recent advances in endoscopic treatment, many T1 colorectal carcinomas are now found and their percentage amenable to endoscopic resection has increased. Endoscopists and pathologists dealing with the steadily increasing number of excised colorectal polyps have to collaborate closely to optimize patient care. Therapeutic management of patients after endoscopic rese...
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
Purpose: The aim of the present study was to evaluate the association of diverticulosis with colorectal polyps, advanced neoplastic lesions (ANLs), and colorectal cancers (CRCs). Methods: The first-time colonoscopy records of 3496 patients were evaluated in this retrospective, cross-sectional cohort study. Data on clinical indications, presence of diverticulosis and diverticulitis, location of diverticula and polps, the size and number of polyps, and results of histopathologic examinations of polypectomies were noted. Categorical data were analyzed with χ2 test or the Fisher exact probability. P-values
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - Category: Surgery Tags: Original Articles Source Type: research
Colorectal polyps such as adenomas and serrated polyps are precursors for colorectal cancer (CRC). Therefore, removal of such polyps reduces CRC risk.1 Patients who had adenomas or serrated polyps removed at colonoscopy are believed to be at increased risk of developing more polyps later in life and eventually CRC.2,3 Thus, colonoscopy surveillance after polyp removal is currently recommended.4
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Commentary Source Type: research
AbstractPurpose of reviewTo elucidate the advantages and limitations of existing artificial intelligence technologies for colonoscopy by evaluating the currently available eight prospective studies (two for automated polyp detection and six for automated polyp characterization).Recent findingsAI is expected to mitigate the inherent risk of human error causing a polyp to be missed or mischaracterized by assisting polyp detection and characterization (i.e., pathological prediction). Some of the prospective studies clearly demonstrate the potential for AI to improve adenoma detection rates, which is considered one of the most...
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research
ConclusionsPatients with advanced colorectal polyps have poor knowledge of personal and familial CRC risk and recommendations. Endoscopists who remove advanced polyps are in an ideal position to educate their patients about their personal risk and the risk and recommendations for first-degree family members.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
CONCLUSIONS: Specific predictors for scheduled screening colonoscopy nonattendance at a safety net hospital can be identified. These findings can be used to tailor community-based interventions to improve colorectal cancer screening rates. PMID: 32149821 [PubMed - as supplied by publisher]
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Gastroenterol Source Type: research
CONCLUSION: This is the first case of an adult UC patient with a solitary juvenile polyp at the 12-year follow-up. The correlation between juvenile polyps and the activity of IBD needs further study. PMID: 32148384 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Conditions:   Colorectal Cancer;   Adenomatous Polyps;   Adenoma;   Advanced Adenoma Interventions:   Diagnostic Test: Multitarget stool FIT-DNA test - ColoClear;   Diagnostic Test: FIT;   Procedure: Colonoscopy Sponsors:   Zhejiang University;   New Horizon Health Technology Co., Ltd;   Beijing Mingze Technology Co., Ltd. Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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