Adult outcomes of childhood bronchiectasis.

Adult outcomes of childhood bronchiectasis. Int J Circumpolar Health. 2020 Dec;79(1):1731059 Authors: Sibanda D, Singleton R, Clark J, Desnoyers C, Hodges E, Day G, Redding G Abstract Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous children from affluent countries; however, there is little information about adult outcomes of childhood bronchiectasis. We reviewed the clinical course of 31 Alaska Native adults 20-40 years of age from Alaska's Yukon Kuskokwim Delta with childhood bronchiectasis. In patients with chronic suppurative lung disease, a diagnosis of bronchiectasis was made at a median age of 4.5 years by computerised tomography (68%), bronchogram (26%), and radiographs (6%). The patients had a median of 75 lifetime respiratory ambulatory visits and 4.5 hospitalisations. As children, 6 (19%) experienced developmental delay; as adults 9 (29%) experienced mental illness or handicap. Four (13%) patients were deceased, four (13%) had severe pulmonary impairment in adulthood, 17 (54%) had persistent or intermittent respiratory symptoms, and seven (23%) were asymptomatic. In adulthood, only five were seen by adult pulmonologists and most had no documentation of a bronchiectasis diagnosis. Lack of provider continuity, remote location and co-m...
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research

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This article reviews the specific imaging features of CF using conventional imaging modalities (chest radiographs and high-resolution computed tomography [HRCT]) as well as emerging imaging technologies (digital chest tomosynthesis and MR imaging). In addition, the authors review the CF-specific HRCT imaging findings that are essential in the evaluation of these patients in the pre –lung transplant and post–lung transplant settings.
Source: Radiologic Clinics of North America - Category: Radiology Authors: Source Type: research
We describe a case of a staphylococcal lung abscess in a teenage girl with CF who presented with a two-week history of non-specific malaise followed by two days of left posterior chest pain and fever. A chest radiograph was consistent with a left sided pulmonary abscess, which was confirmed on a CT scan of the chest. The abscess was drained under ultrasound guidance and cultured methicillin-sensitive Staphylococcus aureus. The patient responded well to antibiotic treatment with the abscess cavity showing complete radiological resolution by six weeks post drainage.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
ConclusionOur specifically trained, radiographer ‐led PICC insertion service proved to be successful. Both straightforward and complex insertions, for example in CF patients could be adequately and efficiently performed.
Source: Journal of Medical Imaging and Radiation Oncology - Category: Radiology Authors: Tags: Medical Imaging —Radiation Oncology—Original Article Source Type: research
The impacts of respiratory viruses in pulmonary exacerbations of CF patientsis not fully understoodMethod: Prospective longitudinal study, 50 CF 6-18 who produce sputum and PEx (2016-2018). Sputum viral respiratory PCR panel, aerobic and fungal culture. Blood count, sedimentation rates and serum C-reactive protein levels were measured and standard spirometry and radiological severity score performed. Additional nasopharyngeal (NP) swab was taken for respiratory virus assessment if clinician considers it necessary.Results: 48.9% sputum samples virus-positive. Human rhinovirus was the most common pathogen (23,4%). Influenza ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric bronchology Source Type: research
BackgroundChronic rhinosinusitis (CRS) is associated with bronchiectasis; however, this relationship has not been well studied in the United States (US) population. In this work we aimed to determine the prevalence of CRS among patients with bronchiectasis affiliated with a US tertiary medical center and identify which comorbid diseases are associated with the presence of CRS in patients with bronchiectasis.MethodsThis was a retrospective cohort study in which data were obtained from a large database warehouse at a tertiary care center. Patients with bronchiectasis were identified from 2007 to 2017 using diagnosis codes fr...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Recent standards of care mention chest radiography (CR) but not chest computed tomography (CT) in routine annual follow-up of children with cystic fibrosis (CF). To minimise radiation risk, CT or CR should only be performed if they impact clinical decision making. We investigated whether in addition to a wide range of commonly used clinical parameters, chest CT and/or CR in routine follow-up of CF patients influence clinical decisions.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Source Type: research
A 30-year-old cystic fibrosis (CF) male with recurrent multi-drug resistant Burkholderia multivorans infections developed persistent bacteremia, despite high-dose antibiotics for>10 days, and ventilator as well as venovenous (VV) extracorporeal membrane oxygenation (ECMO) dependence limiting his transplant candidacy.1,2 No non-pulmonary sources of infection were identified; his chest radiograph demonstrated significant pulmonary disease. We performed bilateral pneumonectomies to clear his infection.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research
A 30-year-old male with cystic fibrosis with recurrent multidrug-resistant Burkholderia multivorans infections developed persistent bacteremia, despite high-dose antibiotics for>10 days and ventilator as well as veno-venous (VV) extracorporeal membrane oxygenation (ECMO) dependence limiting his transplant candidacy.1,2 No non-pulmonary sources of infection were identified; his chest radiograph demonstrated significant pulmonary disease. We performed bilateral pneumonectomies to clear his infection.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: CASE ANECDOTES Source Type: research
Discussion –-       Bronchial atresia usually is benign and asymptomatic and is incidental finding&clinical manifestations may range from recurrent pulmonary infections to mild wheezing and dyspnea. Bronchial atresia is a congenital abnormality resulting from focal interruption of a lobar, segmental, or subsegmental bronchus with associated peripheral mucus impaction (bronchocele, mucocele) and associated hyperinflation of the obstructed lung segment. The apicoposterior segmental bronchus of the left upper lobe is most common site to be involved, followed by segmental bronc...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
CONCLUSION: After more than a decade, lung MRI has become a valuable tool for monitoring CF in clinical routine application and as an endpoint for clinical studies. PMID: 31172247 [PubMed - as supplied by publisher]
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research
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