The effects of vitamin D supplementation on interictal serum levels of calcitonin gene-related peptide (CGRP) in episodic migraine patients: post hoc analysis of a randomized double-blind placebo-controlled trial

ConclusionAccording to the current findings, vitamin D supplementation in episodic migraineurs, particularly in those with migraine with aura, may potentially improve migraine headache characteristics and disability probably through attenuating CGRP levels. Therefore, these results could provide a new insight into anti-nociceptive effects of vitamin D; however, more studies are required to confirm our findings.Trial registrationThe trial is registered in the Iranian registry of clinical trials (IRCT) at 11 July 2018, with IRCT code:IRCT20151128025267N6.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research