Atherosclerosis Immunoimaging by Positron Emission Tomography.

Atherosclerosis Immunoimaging by Positron Emission Tomography.
Arterioscler Thromb Vasc Biol. 2020 Feb 06;:ATVBAHA119313455
Authors: Pérez-Medina C, Fayad ZA, Mulder WJM
Abstract
The immune system's role in atherosclerosis has long been an important research topic and is increasingly investigated for therapeutic and diagnostic purposes. Therefore, noninvasive imaging of hematopoietic organs and immune cells will undoubtedly improve atherosclerosis phenotyping and serve as a monitoring method for immunotherapeutic treatments. Among the available imaging techniques, positron emission tomography's unique features make it an ideal tool to quantitatively image the immune response in the context of atherosclerosis and afford reliable readouts to guide medical interventions in cardiovascular disease. Here, we summarize the state of the art in the field of atherosclerosis positron emission tomography immunoimaging and provide an outlook on current and future applications.
PMID: 32078338 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 5, 2020 Category: Cardiology Authors: Pérez-Medina C, Fayad ZA, Mulder WJM Tags: Arterioscler Thromb Vasc Biol Source Type: research