Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR.

Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR. J Korean Med Sci. 2020 Feb 17;35(6):e79 Authors: Lim J, Jeon S, Shin HY, Kim MJ, Seong YM, Lee WJ, Choe KW, Kang YM, Lee B, Park SJ Abstract Since mid-December of 2019, coronavirus disease 2019 (COVID-19) infection has been spreading from Wuhan, China. The confirmed COVID-19 patients in South Korea are those who came from or visited China. As secondary transmissions have occurred and the speed of transmission is accelerating, there are rising concerns about community infections. The 54-year old male is the third patient diagnosed with COVID-19 infection in Korea. He is a worker for a clothing business and had mild respiratory symptoms and intermittent fever in the beginning of hospitalization, and pneumonia symptoms on chest computerized tomography scan on day 6 of admission. This patient caused one case of secondary transmission and three cases of tertiary transmission. Hereby, we report the clinical findings of the index patient who was the first to cause tertiary transmission outside China. Interestingly, after lopinavir/ritonavir (Kaletra, AbbVie) was administered, β-coronavirus viral loads significantly decreased and no or little coronavirus titers were observed. PMID: 32056407 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

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CONCLUSION: The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity. Viral shedding from URT was high from the prodromal phase. Radiological pneumonia was common from the early days of illness, but it was frequently not evident in simple CXR. These findings could be plausible explanations for the easy and rapid spread of SARS-CoV-2 in the community. PMID: 32242348 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
This study, in the same high-tier journal, claims that the sensitivity of CT is 98% vs a sensitivity of 70% for viral PCR. They say: “Our results support the use of chest CT for screening for COVD-19** for patients with clinical and epidemiologic features compatible with COVID-19 infection particularly when RT-PCR testing is negative.” With a statement as strong as that, surely they are saying that they have evidence that CT can be applied broadly? They even mention patients with epidemiological features of infection … that is to say, folks who have been exposed but don’t have symptoms. He...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Artificial Intelligence COVID-19 Health Tech Physicians Research CT Luke Oakden-Rayner Radiology Source Type: blogs
Vidur Mahajan Vasanth Venugopal By VASANTH VENUGOPAL MD and VIDUR MAHAJAN MBBS, MBA What can Artificial Intelligence (AI) do? AI can, simply put, do two things – one, it can do what humans can do. These are tasks like looking at CCTV cameras, detecting faces of people, or in this case, read CT scans and identify ‘findings’ of pneumonia that radiologists can otherwise also find – just that this happens automatically and fast. Two, AI can do things that humans can’t do – like telling you the exact time it would take you to go from point A to point B (i.e. Google maps), or like ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Artificial Intelligence COVID-19 Health Tech AI coronavirus CT scans Pandemic Radiology Vasanth Venugopal Vidur Mahajan Source Type: blogs
A  paperrecently published in theAmerican Journal of Roentgenologyhas found that scans of patients with COVID-19 share many similarities with imaging studies of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). According to the World Health Organization (WHO), the  pandemichas so far (as of the date of this article) resulted in over 191,000 cases and more than 7,800 deaths. Although most of those infected only have cold-like symptoms, about 16 percent are serious cases where patients suffer from pneumonia and breathing difficulties. Coronavirusesare responsible for bo...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
CT scans revealed rapid progression of abnormalities in COVID-19 patients,...Read more on AuntMinnie.comRelated Reading: CT details effect of COVID-19 on pregnant women CT illuminates COVID-19 in Diamond Princess cases 3 factors linked to risk of death from coronavirus Radiologists distinguish COVID-19 pneumonia on CT CT findings for coronavirus may overlap with adenovirus
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Scans show no aggravation of symptoms.
Source: Diagnostic Imaging - Category: Radiology Authors: Tags: Complications of Pregnancy Coronavirus Infectious Diseases & Conditions/COVID-19 Pregnancy and Birth Source Type: news
Ultrasound scans show promise for helping to monitor patients with COVID-19,...Read more on AuntMinnie.comRelated Reading: ACR Data Science Institute publishes COVID-19 AI use case Study outlines 1st person-to-person coronavirus spread CT shows pneumonia patterns in kids with coronavirus 3 factors linked to risk of death from coronavirus Radiologists distinguish COVID-19 pneumonia on CT
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractThere is a new public health crises threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province, China in December 2019. There have been around 96,000 reported cases of coronavirus disease 2019 (COVID-2019) and 3300 reported deaths to date (05/03/2020). The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usu...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Cheryl Man is usually the only one wearing a face mask on her New York City subway train. She notices this, but other people on the train notice, too. Usually she just gets odd stares from other commuters. But on Tuesday morning, when she was walking to school, a group of teens jeered at her and coughed in her direction. “I felt very humiliated and misunderstood,” says Man, a 20-year-old student and research assistant who is ethnically Chinese. Man also feels the stigma at her workplace, where she keeps her mask on. None of her colleagues wear a face mask, and some of them have asked her if she is sick. &ldqu...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 onetime overnight Source Type: news
This article is republished from The Conversation. Read the original article. The post Coronavirus: Ten Reasons Why You Ought Not to Panic appeared first on Inter Press Service. Excerpt: Ignacio López-Goñi is microbiologist and works in University of Navarra (Spain). The post Coronavirus: Ten Reasons Why You Ought Not to Panic appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Coronavirus Source Type: news
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