Ivermectin Augments the In Vitro and In Vivo Efficacy of Cisplatin in Epithelial Ovarian Cancer by Suppressing Akt/mTOR Signaling.

CONCLUSIONS: Our work suggests that ivermectin may be a useful addition to the treatment armamentarium for ovarian cancer and that targeting Akt/mTOR signaling is a therapeutic strategy to increase chemosensitivity in ovarian cancer.
PMID: 32039764 [PubMed - in process]

Source: The American Journal of the Medical Sciences - January 31, 2020 Category: General Medicine Authors: Zhang X, Qin T, Zhu Z, Hong F, Xu Y, Zhang X, Xu X, Ma A Tags: Am J Med Sci Source Type: research