Emergent measles-containing vaccination recommendation for aged 6-11  months and detection of vaccine-associated measles during a large measles outbreak in Okinawa, Japan, in 2018.

Emergent measles-containing vaccination recommendation for aged 6-11 months and detection of vaccine-associated measles during a large measles outbreak in Okinawa, Japan, in 2018. Vaccine. 2020 Feb 06;: Authors: Kuba Y, Kyan H, Iha Y, Kato T, Oyama M, Miyahira M, Kakita T, Takara T, Yamauchi M, Kamiya H, Sunagawa T, Kawakami Y, Nidaira M, Kudaka J, Yamakawa M, Itokazu T, Itokazu K Abstract Okinawa Prefecture, Japan, experienced a large measles outbreak from March to May 2018. During this outbreak, there were 99 laboratory-confirmed cases and 14 vaccine-associated measles cases. In addition to the reinforcement of routine immunization, Okinawa prefectural government introduced emergent measles-containing vaccination recommendations for infants aged 6-11 months as part of the outbreak response. Increased concern exists in Okinawa about measles in infants following a previous outbreak from 1998 to 2001, when nine children including four infants died. Of 8062 infants aged 6-11 months who received measles-containing vaccine (MCV), six developed vaccine-associated measles; incidence was 0.74 per 1000 doses (95%CI 0.27-1.62). This was similar to that of first dose routine immunization recipients at one year of age (IR 0.60, 95%CI 0.20-1.78). Among 14 vaccine-associated measles cases, throat swab samples showed the highest positive rate (92.9%) by real-time reverse transcription polymerase chain reaction (RT-qPCR), followed by urine (25.0%) and wh...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research

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Since 2016, large scale measles outbreaks have heavily affected countries across Europe. In England, laboratory confirmed measles cases increased almost four-fold between 2017 and 2018, from 259 to 966 cases.
Source: BMC Public Health - Category: Consumer Health News Authors: Tags: Research article Source Type: research
CONCLUSIONS: Changing epidemiology of measles means distinguishing between wild-type and vaccine-strain measles has become a new challenge. Implications for public health: The reflection of the public health management of this case has provided a valuable teaching tool for public health professionals globally, particularly in low incidence measles countries. PMID: 32190947 [PubMed - as supplied by publisher]
Source: Australian and New Zealand Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Aust N Z J Public Health Source Type: research
Abstract Despite high coverage with measles, mumps, and rubella vaccine in the United States, outbreaks of mumps occur in close contact settings such as schools, colleges, and camps. Starting in late 2015, outbreaks were reported from several universities, and by the end of 2017, greater than 13,800 cases had been reported nation-wide. In 2013, the CDC and the Association of Public Health Laboratories contracted four Vaccine Preventable Diseases Reference Centers (VPD-RCs) to perform real-time reverse transcription PCR (RT-qPCR) to detect mumps RNA in clinical samples and to determine the genotype. Twelve genotype...
Source: Virus Research - Category: Virology Authors: Tags: Virus Res Source Type: research
Ministers look to have given up on containment in favour of a novel approach some experts are wary ofCoronavirus: latest updatesHerd immunity is a phrase normally used when large numbers of children have been vaccinated against a disease like measles, reducing the chances that others will get it. As a tactic in fighting a pandemic for which there is no vaccine, it is novel – and some say alarming.It relies on people getting the disease – in this case Covid-19 – and becoming immune as a result. Generally it is thought that those who recover will be immune, at least for now, so they won’t get it twice.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Infectious diseases Microbiology Science World news Society Medical research UK news Source Type: news
This paper concludes the importation of measles and vaccination delays among young children led to an outbreak of measles in New York City. The outbreak response was resource intensive and caused serious illness, particularly among unvaccinated children.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
ConclusionsIn this study, we have identified high-risk communities that are typically obscured in county-level risk assessments and found that public schools, like private schools, are exhibiting predictable increases in vaccination exemption percentages. As public health agencies confront the reemerging threat of measles and other vaccine-preventable diseases, findings such as ours can guide targeted interventions and surveillance within schools, cities, counties, and sociodemographic subgroups.
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Conclusion: The measles outbreak in the gold-mining areas in Abu Hamad had serious consequences attributed to poor environmental conditions, overcrowding, poor nutrition and lack of vaccination. The health authority response helped end the outbreak. The local health authority should consider the gold-mining areas as a potential risk to public health in their future plans. PMID: 32141592 [PubMed - in process]
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
Abstract SUMMARYMumps is an acute viral infection characterized by inflammation of the parotid and other salivary glands. Persons with mumps are infectious from 2 days before through 5 days after parotitis onset, and transmission is through respiratory droplets. Despite the success of mumps vaccination programs in the United States and parts of Europe, a recent increase in outbreaks of mumps virus infections among fully vaccinated populations has been reported. Although the effectiveness of the mumps virus component of the measles-mumps-rubella (MMR) vaccine is suboptimal, a range of contributing factors has led t...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
TTP, a technology company based in Melbourn, UK, is developing a handheld PCR (polymerase chain reaction) diagnostic device that can rapidly detect influenza viruses, and one day other viruses, in samples of nasal mucus. The company claims that the s...
Source: Medgadget - Category: Medical Devices Authors: Tags: Diagnostics Exclusive Public Health Source Type: blogs
This NIHR Signal pooled data from 56 studies and found that the vaccine is around 58% effective when administered before nine months compared with 83% after nine months.With measles on the rise in Europe and the UK, it is helpful to know that in the event of a measles outbreak, it could be used safely in younger infants as an additional measure.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
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