Effect of Physical Exercise Training in Patients With Chagas Heart Disease (From the PEACH STUDY)

Chagas disease is an infection caused by Trypanosoma cruzi, with cardiac involvement in 25-30% in the chronic phase as a result of an inflammatory process which leads to cell death, fibrosis, and cardiac remodeling 1. Recent guidelines recommend regular physical activity and structured exercise training as a complementary therapy in cardiac patients 2. However, only few studies have evaluated the effect of exercise training in patients with Chagas heart disease (HD). Considering the worst prognosis of Chagas HD when compared to other etiologies3, randomized clinical trials are needed to investigate the effects of exercise training in patients with Chagas HD.

Source: The American Journal of Cardiology - February 9, 2020 Category: Cardiology Authors: Fernanda de Souza Nogueira Sardinha Mendes, Mauro Felippe Felix Mediano, Fernando Cesar de Castro e Souza, Paula Simpl ício da Silva, Fernanda Martins Carneiro, Marcelo Teixeira de Holanda, Roberto Magalhães Saraiva, Sergio Salles Xavier, Pedro Emmanuel Source Type: research