PIM1, CYP1B1, and HSPA2 Targeted by Quercetin Play Important Roles in Osteoarthritis Treatment by Achyranthes bidentata.

Conclusion: The docking of PIM1-quercetin, CYP1B1-quercetin, and HSPA2-quercetin may play important roles during the treatment of osteoarthritis by Achyranthes bidentata. PMID: 31998395 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

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The Journal of Alternative and Complementary Medicine, Ahead of Print.
Source: The Journal of Alternative and Complementary Medicine - Category: Complementary Medicine Authors: Source Type: research
N, Bruyère O, Rizzoli R, Kanis JA, Reginster JY Abstract Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for this reason, are often only afforded brief reference (or completely excluded) from current OA guidelines. Thus, the aim of this review was to synthesize the current evidence regarding autologous chondrocyte implantation (ACI), mesenchymal s...
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Background: Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. The most common treatment for KOA is non-steroidal anti-inflammatory drug administration. However, the analgesic effect is limited and often accompanied by multiple side effects. Hence, many KOA patients opt for complementary and alternative medicine. Acupuncture is one of the most popular complementary treatments with great analgesic effect and minimal side effect. Electroacupuncture (EA...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Abstract Context: Clinical studies suggest that AL-TENS, acupuncture-like transcutaneous electrical nerve stimulation (TENS), is effective for treating many types of pain and physical dysfunction. To date, only a few studies have compared the TENS and AL-TENS forms of stimulation, and no studies have compared the efficacy of conventional TENS and AL-TENS in patients who have undergone total knee arthroplasty (TKA). Objectives: The study intended to determine (1) the efficacy of conventional TENS and AL-TENS for TKA patients and (2) which outcomes-pain at rest, movement-evoked pain, and physical function-were ...
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research
(Natural News) Researchers from hospitals affiliated with Jining University and Jilin University in China investigated whether tai chi chuan (TCC) exercises can improve functional outcomes and the quality of life (QOL) of patients with primary total knee arthroplasty (TKA) due to knee osteoarthritis (OA). Their findings were published in the journal Complementary Therapies in Clinical Practice....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Zheng Y, Duan X, Qi S, Hu H, Wang M, Ren C, Xu H, Quan R Abstract Objective: This meta-analysis aimed to investigate the effectiveness of acupuncture therapy plus hyaluronic acid injection versus hyaluronic acid injection alone for patients with knee osteoarthritis. Methods: Relevant randomized controlled trials that compared the combined effect of acupuncture therapy and hyaluronic acid injection with hyaluronic acid injection alone for knee osteoarthritis patients were included. 10 studies were included in this meta-analysis, and the relative risk (RR) and weight mean difference (MD) with 95% CI for ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
The Journal of Alternative and Complementary Medicine, Ahead of Print.
Source: The Journal of Alternative and Complementary Medicine - Category: Complementary Medicine Authors: Source Type: research
Chondrocyte apoptosis activated by the mitochondrial dependent pathway serves a crucial role in cartilage degeneration of osteoarthritis (OA). In the present study, the protective effects of CMCS against sodiu...
Source: BMC Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Tags: Research article Source Type: research
Corrigendum to "Efficacy Comparison of Five Different Acupuncture Methods on Pain, Stiffness, and Function in Osteoarthritis of the Knee: A Network Meta-Analysis". Evid Based Complement Alternat Med. 2019;2019:3713197 Authors: Li S, Xie P, Liang Z, Huang W, Huang Z, Ou J, Lin Z, Chai S Abstract [This corrects the article DOI: 10.1155/2018/1638904.]. PMID: 31915444 [PubMed - in process]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Huang H, Pan J, Yang W, Han Y, Luo M, Liang H, Zeng L, Liang G, Lin J, Liu J Abstract Objective: To compare the efficacy and safety of kidney-tonifying and blood-activating medicinal herbs (KTBAMs) and nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of knee osteoarthritis (KOA). Methods: Randomized controlled trials (RCTs) from online databases that compared the efficacy of KTBAMs and NSAIDs in the treatment of KOA were retrieved. The main outcomes included the evaluation of functional outcomes, pain, and adverse effects. The Cochrane risk-of-bias (ROB) tool was used to assess methodolog...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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