Successful liver transplant from a hemophilia A donor with no development of hemophilia A in recipient.

We present a case of liver transplantation in a hemophilia A donor to a recipient with no history of hemophilia A with literature review. To our knowledge, this is only the second case in humans of hemophilia A patient as a donor in liver transplantation. PMID: 31997485 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Tags: J Thromb Haemost Source Type: research

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French researchers have identified three key MRI biomarkers to heighten the...Read more on AuntMinnie.comRelated Reading: CE-MRI with CT extends life for patients with liver cancer MRI scoring system could predict liver transplant need MRI-guided cryoablation a boon for HCC patients CBCT-guided radiotherapy shows promise for HCC Contrast US clears up indeterminate HCC cases on MRI
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Purpose of review Retinal detachment initiates a series of events that lead to degenerative changes in retinal synaptic architecture as well as the well-known phenomena of gliosis and photoreceptor apoptosis. Retinal reattachment does not always result in complete visual recovery, even if the fovea is not directly involved in the detachment. Rho-kinase (ROCK) inhibitors may mitigate some of these deleterious changes including disruption of synaptic architecture, photoreceptor apoptosis, and initiation of the epithelial-mesenchymal transition that characterizes proliferative vitreoretinopathy (PVR). This review focuses on...
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: TRANSLATIONAL RESEARCH: Edited by Jason Hsu and Sunir J. Garg Source Type: research
Authors: Battisha A, Sawalha K, Madoukh B, Sheikh O, Doughem K, Al-Akchar M, Al-Sadawi M, Shaikh S Abstract Systemic Mastocytosis (SM) is a disorder of excessive mast cell infiltration in multiple organ tissues. Atherosclerosis is a major risk factor for developing acute coronary syndrome [1]. In addition to lipid accumulation in the arterial wall, inflammation plays an important role in the pathogenesis of plaque rupture and activating the thrombosis cascade [2]. The Mast cells contribution to plaque destabilization has been well established in multiple animal and human studies [3]. In a recent study, SM has been ...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Publication date: Available online 18 February 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): M. Susan Mandell, Jiapeng Huang, Jing Zhao
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Authors: Iwamoto J, Murakami M, Monma T, Ueda H, Tamamushi M, Konishi N, Yara SI, Hirayama T, Ikegami T, Honda A, Mizokami Y Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA) are the most common causes of drug-induced gastroduodenal ulcer and We investigated preventive treatment with use of concomitant anti-ulcer drugs and the clinical features of gastroduodenal ulcer in cases treated with these drugs. Patients with gastroduodenal ulcer and patients with bleeding were classified into 3 groups: LDA, non-aspirin NSAIDs, and those taking neither aspirin nor NSAIDs. Chronological changes...
Source: Journal of Clinical Biochemistry and Nutrition - Category: Nutrition Tags: J Clin Biochem Nutr Source Type: research
AbstractThrombocytopenia is a common complication of critical care patients. The rates of bleeding events and mortality are also significantly increased in critical care patients with thrombocytopenia. Therefore, the Critical Care Medicine Committee of Chinese People ’s Liberation Army (PLA) worked with Chinese Society of Laboratory Medicine, Chinese Medical Association to develop this consensus to provide guidance for clinical practice. The consensus includes five sections and 27 items: the definition of thrombocytopenia, etiology and pathophysiology, diagnos is and differential diagnosis, treatment and prevention.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research
CONCLUSION: The rule-based HLA genotype extraction method shows reliable accuracy. We believe that there are significant number of patients who takes profit when this under-used genetic information will be return to them. PMID: 32233158 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Performing endoscopy during the first six hours after a patient with gastrointestinal bleeding is handed off to a specialist does not lower the 30-day mortality rate compared to procedures done six to 24 hours after consultation, according to a new study of 516 volunteers reported in Thursday's New England Journal of Medicine.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Major transplant centres have stopped performing many of their procedures due to the coronavirus pandemic, while the national coordinating body says a complete cessation “may only be days away”.
Source: HSJ - Category: UK Health Source Type: news
Condition:   Allogeneic Hematopoietic Cell Transplantation Intervention:   Drug: Nicotinamide riboside (NR) Sponsor:   Case Comprehensive Cancer Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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