Chromosome 15q BP3 to BP5 deletion is a likely locus for speech delay and language impairment: Report on a four ‐member family and an unrelated boy

ConclusionThis report, along with other recent observations, suggests the hypothesis that the BP region comprised between BP3 and BP5 in chromosome 15q13 is involved in several brain human dysfunctions, including impairment of the language development and, its deletion, may be directly or indirectly responsible for the speech delay and language deficit in the affected individuals.

Source: Molecular Genetics & Genomic Medicine - January 27, 2020 Category: Genetics & Stem Cells Authors: Piero Pavone, Martino Ruggieri, Simona D. Marino, Giovanni Corsello, Xena Pappalardo, Agata Polizzi, Enrico Parano, Catia Romano, Silvia Marino, Andrea Domenico Pratic ò, Raffaele Falsaperla Tags: ORIGINAL ARTICLE Source Type: research