The role of the FPR2/ALX receptor in atherosclerosis development and plaque stability

Conclusion FPR2/ALX is proatherogenic due to effects on bone marrow-derived cells, but promoted a more stable plaque phenotype through effects on SMCs. Taken together, these results suggest a dual role of FPR2/ALX signalling in atherosclerosis by way of promoting disease progression and but increasing plaque stability.

http://cardiovascres.oxfordjournals.org/cgi/content/short/105/1/65?rss=1

Source: Cardiovascular Research - December 26, 2014 Category: Cardiology Authors: Petri, M. H., Laguna-Fernandez, A., Gonzalez-Diez, M., Paulsson-Berne, G., Hansson, G. K., Back, M. Tags: Vascular biology Source Type: research