miR-340 reduces accumulation of amyloid- β through targeting BACE1 (β-site amyloid precursor protein cleaving enzyme 1) in Alzheimer' s disease.

CONCLUSION: MiR-340 was down-regulated in AD and educed accumulation of amyloid-βthrough targeting BACE1, suggesting a potential therapeutic target for AD. PMID: 31957613 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31957613?dopt=Abstract

Source: Current Neurovascular Research - January 15, 2020 Category: Neurology Authors: Tan X, Luo Y, Pi D, Xia L, Li Z, Tu Q Tags: Curr Neurovasc Res Source Type: research