Review of Comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice

AbstractHidradenitis suppurativa (HS) is a chronic, recurrent skin inflammatory disease associated with a variety of comorbidities, like reduced quality of life, metabolic syndrome, sexual dysfunction, working disability, axial spondyloarthritis, inflammatory bowel disease, depression, and anxiety. Like psoriasis, HS patients have been found to have higher risk of cardiovascular death and suicide risk. Clinicians should be informed about these comorbidities so that appropriate screening is implemented. All this evidence suggests that for such a chronic, multi-comorbid disease, the use of validated outcomes to assess severity and effect of treatment, along with the use of clinically important patient reported outcomes, is essential. The potential of available treatments to negatively and positively affect these comorbidities should also be taken into account when designing treatment strategies. This review provides an outline of important HS comorbidities with emphasis on possible implications for daily clinical practice.
Source: Dermatology and Therapy - Category: Dermatology Source Type: research

Related Links:

Publication date: Available online 20 February 2020Source: Catalysis TodayAuthor(s): Thi Phuong Thao Nguyen, Ki Hyuck Yang, Moon Hyeon Kim, Yong Seok HongAbstractFe2O3-promoted V2O5-WO3/TiO2 catalysts with high Fe2O3-to-V2O5 ratios (3.4 – 6) have been prepared for the selective reduction of NO with NH3 (NH3-SCR) and extensively characterized using various spectroscopic measurements. No crystalline iron oxides were indicated even for 8% Fe2O3-promoted V2O5-WO3/TiO2 but distorted α-Fe2O3 crystallites were observed in a XRD pattern for 7.04% Fe2O3-promoted WO3/TiO2. Both Raman and XPS measurements suggest the form...
Source: Catalysis Today - Category: Chemistry Source Type: research
Publication date: Available online 20 February 2020Source: MethodsXAuthor(s): Luis O. Soto-Rojas, Cecilia Bañuelos, Linda Garces-Ramirez, Claudia Luna-Herrera, Yazmin M. Flores-Martínez, Guadalupe Soto-Rodríguez, Bismark Gatica-García, Francisco E. López-Salas, José Ayala-Dávila, María E. Gutiérrez-Castillo, América Padilla-Viveros, Fidel de la Cruz-López, Irma A. Martínez-Davila, Daniel Martinez-FongAbstractAn animal model, suitable for resembling Parkinson's disease (PD) progress, should show both, motor and non-motor alterations. However...
Source: MethodsX - Category: Science Source Type: research
ABSTRACT: Objectives: To estimate the magnitude of gender differences in disability among adults aged 60 and older and to evaluate whether they can be associated with social gender inequality and socioeconomic contextual factors at the level of Brazilian federative units. Methods: This is a multilevel study that used data from 23,575 older adults of 27 federative units who participated in the 2013 Brazilian Health Survey. The activity limitation index was developed from the item response theory, using activities of daily living and instrumental activities of daily living variables. The association of individual and context...
Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
ABSTRACT: Introduction: In high-income countries, persons of high socioeconomic status (SES) have a lower cardiovascular risk. However, in middle and low-income countries, the results are controversial. Objective: To evaluate the association between family income and cardiovascular risk factors in young adults. Methods: A total of 2,063 individuals of a birth cohort initiated in 1978/79 in the city of Ribeir ão Preto, Brazil, were evaluated at age of 23/25 years. Cardiovascular risk factors (hypertension, sedentary lifestyle, smoking, low high-density lipoprotein (HDL)-cholesterol, high low-density lipoprotein (LDL)...
Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
Publication date: Available online 21 February 2020Source: Molecular Genetics and MetabolismAuthor(s): Gabriella A. Horvath, Robert M. Stowe, Carlos R. Ferreira, Nenad BlauAbstractPsychiatric symptoms are common manifestations in many inborn errors of metabolism (IEMs), ranging from attention deficit, anxiety and mood and behavioral disorders to psychosis. Furthermore, IEMs represent a significant percentage of all autism cases. We reviewed and updated the list of metabolic disorders known to be associated with various psychiatric manifestations and found more than 100 relevant IEMs. This represents the third of a series o...
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
ConclusionOrganisational factors of safety climate, disability management and labour management processes appear to be associated with work injury and location of work within this workplace. The role of organisational factors should be considered in future studies examining interventions aimed at addressing work injury.
Source: Safety Science - Category: Occupational Health Source Type: research
Recent evidence indicates that reactivated memories are malleable and can integrate new information upon their reactivation. We injected rats with oxytocin to investigate whether the delivery of a drug which dampens anxiety and fear before the reactivation...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Adolescents with diabetes are at increased risk for depression and anxiety, which when untreated negatively affects diabetes control. During a 6-month period, the Patient Health Questionnaire for Depression and Anxiety (PHQ-4) screening tool was utilized. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
OBJECTIVE: Multiple cognitive risks from different theoretical paradigms (dysfunctional attitudes, negative inferential style, self-criticism, dependency, brooding) predict depression, but may be transdiagnostic vulnerabilities for multiple psychopathologi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
PURPOSE: To evaluate the association between cancer diagnosis and depression and suicidal ideation in a population-based cohort in the United States. METHODS: This was a cross-sectional study based on the National Health and Nutrition Examination S...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
More News: Anxiety | Cardiology | Cardiovascular | Depression | Dermatology | Disability | Heart | Hidradenitis | Inflammatory Bowel Disease | Metabolic Syndrome | Psoriasis | Sexual Dysfunction | Skin | Suicide