Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones

ConclusionsPediatric nephrologists have an important role in the diagnostic work-up and prevention of recurring nephrolithiasis.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research

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A new trend called 'dry-fasting' encourages followers to completely give up drinking water, but health experts say it could lead to dehydration, urinary tract infections and kidney stones.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Ureteritis cystica is rare, benign entity that associates with chronic urothelial irritation such as recurrent urinary tract infection or nephrolithiasis. It is often diagnosed incidentally on routine imaging or ureteroscopy in asymptomatic individuals. In this case report, we present the retrograde pyelogram and ureteroscopy images of a rare case of extensive unilateral ureteritis cystica in a 78-year-old female presenting for elective stone surgery.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
We report a large mobile bladder calculus with intense 99mTc-MDP uptake demonstrated on both whole-body bone scintigraphy and SPECT/CT images in a patient with complicated chronic history of urolithiasis and urinary tract infection. Bone tracer uptake in bladder calculus is a rare phenomenon and might be related to the composition and matrix of calculus, direct exposure to excreted radiotracer, and bacterial colonization on the surface of calculus.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Publication date: Available online 24 November 2019Source: Actas Urológicas Españolas (English Edition)Author(s): Baochao Zhang, Haijie Xie, Chunyu LiuAbstractIntroduction and objectivesThe study was conducted to identify the risk factors of upper tract stone formation in patients with diversions after radical cystectomy (RC).Materials and methodsAll patients with diversion after RC were collected in our center from January 2005 to December 2013. Three different common diversions were included: Orthotopic neobladder (ON: 168 patients), Ileal Conduit (IC: 93 patients) or Ureterocutaneostomy (UC: 104 patients)....
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research
PurposeAbstractTo determine if treatment of non-obstructing urolithiasis is effective in management of recurrent UTI.Materials and methodsA retrospective review was performed of patients undergoing elective management of non-struvite upper tract urinary calculi with recurrent UTI from 2009 to 2016. Recurrent UTI was defined at  ≥ 3 UTI in 12 months, with symptoms and documented urine culture. Preoperative CT was performed in all patients to determine stone burden. All patients had postoperative imaging and ≥ 12 months of follow-up. Pre- and postoperative variables were between pa...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Authors: Imam TH, Patail H, Patail H Abstract Medullary Sponge Kidney (MSK) disease is a rare congenital malformation of the distal nephron where cystic dilatation is appreciable in the collecting ducts and renal papillae. Most cases of the malformation are thought to arise from a malfunction within neurotrophic factor and tyrosine kinase interactions. Presentation and prognosis are usually indolent; however, they include urinary tract infections (UTI), nephrolithiasis and nephrocalcinosis, distal renal tubular acidosis (dRTA) and hypocitraturia. With an insidious and asymptomatic onset, MSK is a difficult renal ma...
Source: International Journal of Nephrology and Renovascular Disease - Category: Urology & Nephrology Tags: Int J Nephrol Renovasc Dis Source Type: research
ConclusionsWe found that PH3 was significantly diagnosed in our urolithiasis patients during childhood. Nine novel HOGA1 mutations were identified in association with PH3, which provide a first-line investigation in Chinese PH3 patients. The eGFR was normal in all children with PH3. This finding is in contrast to the early impairment of renal function in PH1 and PH2.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsUse of antibiotics for more than 2 months in early adulthood and middle age is associated with higher risk for urinary stone disease in later life.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
An 82-year-old male, with a history of bowel cancer with partial colectomy, gastroesophageal reflux disease, remote partial gastrectomy for peptic ulcer disease, and no documented prior kidney disease, presents with several months of fatigue and subacute decline in kidney function. He had no history of diabetes, hypertension, kidney stones, or prior urinary tract infections. He denied use of nonsteroidal anti-inflammatory agents, herbal medications, and recent antibiotics. There was no family history of renal disease.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Make Your Diagnosis Source Type: research
Purpose of review Uromodulin (UMOD), also known as Tamm–Horsfall protein, is the most abundant protein in human urine. UMOD has multiple functions such as protection against urinary tract infections and nephrolithiasis. This review outlines recent progress made in UMOD's role in renal physiology, tubular transport, and mineral metabolism. Recent findings UMOD is mostly secreted in the thick ascending limb (TAL) and to a lesser degree in the distal convoluted tubule (DCT). UMOD secretion is regulated by the calcium-sensing receptor. UMOD upregulates ion channels [e.g., renal outer medullary potassium channel, tra...
Source: Current Opinion in Nephrology and Hypertension - Category: Urology & Nephrology Tags: MOLECULAR CELL BIOLOGY AND PHYSIOLOGY OF SOLUTE TRANSPORT: Edited by Vivek Bhalla and Alan C. Pao Source Type: research
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