Four-Year Longitudinal Study of Motor and Non-motor Symptoms in LRRK2-Related Parkinson's Disease

Conclusions: PD gene risk variant carriers were more likely to progress faster in their motor severity than non-carriers. There were transient differences in certain non-motor symptoms and quality of life in carriers. However, more studies are warranted to assess the association of PD risk variants and progression of non-motor symptoms.

https://www.frontiersin.org/articles/10.3389/fneur.2019.01379

Source: Frontiers in Neurology - January 16, 2020 Category: Neurology Source Type: research