Impact of Maternal Smoking Associated Lyso-phosphatidylcholine 20:3 on Offspring Brain Development
Publication date: Available online 15 January 2020Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Lu Yong-Ping, Christoph Reichetzeder, Cornelia Prehn, Liang-Hong Yin, Chang Chu, Saban Elitok, Bernhard K. Krämer, Jerzy Adamski, Berthold HocherAbstractMaternal smoking during pregnancy affects fetal neurological development. Metabolomic studies in the general population suggest that smoking is associated with characteristic metabolic alterations. We investigated the association between the maternal smoking status, the fetal metabolome and head circumference at birth, as a surrogate parameter of brain development. 320 mother/newborn pairs of the Berlin Birth Cohort were investigated. Anthropometric parameters, including head circumference, of newborns of smoking mothers, former smoking mothers, and never smoking mothers were compared to assess the impact of maternal smoking behavior. Associations between maternal smoking behavior and 163 cord blood metabolites and associations between newborn head circumference and concentrations of smoking behavior related metabolites were analyzed. Male newborns of smoking mothers had a reduced head circumference when compared with newborns from former smoking and never smoking mothers (p
Conclusion: Decidual vasculopathy at term contains the same CD56 positive extravillous endovascular trophoblasts seen with spiral artery remodeling in early pregnancy. CD56 may serve as a possible marker for decidual vasculopathy in the later stages of pregnancy. PMID: 32068473 [PubMed - as supplied by publisher]
Authors: PMID: 32066585 [PubMed - in process]
Publication date: March 2020Source: The Lancet Global Health, Volume 8, Issue 3Author(s): Stijn Van Hees, Stephen Raimon, Joseph Nelson Siewe Fodjo, Robert Colebunders
The aim of this study is to explore factors that determine infant removal by Child Protective Services and placement in out of home care, for methamphetamine-using women receiving pregnancy care with Western Australia Women and Newborn Drug and Alcohol Ser...
BACKGROUND: Trauma is the leading cause of non-obstetric death in pregnancy. While maternal management is defined, few studies have examined the effects on the fetus. METHODS: Following IRB approval, all pregnant females (2010-2017) at a level-1 tr...
ConclusionDelayed postintubation tracheal stenosis should be taken into consideration, when a patient suffers from suffocating tracheal stenosis.
Conditions: Gastric Ultrasound; Fasting ( 6H for Solid ; 2H for Clear Fluid ); Pregnant Women Intervention: Sponsor: University Hospital, Montpellier Not yet recruiting
Condition: Pregnancy Intervention: Device: Ultrasonography Sponsor: Lawson Health Research Institute Completed
Conditions: Type 1 Diabetes; Pregnancy in Diabetic Intervention: Sponsors: Ana Braescu; University of Arizona Terminated
Conditions: Pregnancy Related; Anemia, Iron Deficiency; Anemia of Pregnancy Interventions: Drug: Ferumoxytol; Drug: Ferrous Sulfate Sponsors: Thomas Jefferson University; Auerbach Hematology and Oncology Not yet recruiting