Effect Of Botulinum Toxin Type-A In Spasticity And Functional Outcome Of Upper Limbs In Cerebral Palsy

ConclusionI.m. BTX-A injected using anatomical landmarks had significant improvement in both clinical and functional outcome measures. We noticed significant improvement in MACS and COPM at 6 months despite return of local spasticity. It is safe and effective for spasticity of upper limbs in cerebral palsy and capable of improving function without major side effects. MACS & COPM are easy to use, less time consuming & easily adjusted to local needs. Randomized control trials with long follow up are required in future with special focus on dosing and timing, scoring system for functional outcome as per regional needs and issue for antibody formation for repeat injections of BTX-A.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research