A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis

Conclusions
FACETS is effective in reducing fatigue severity and increasing fatigue self-efficacy. However, it is difficult to assess the additional cost in terms of cost-effectiveness (ie, cost per QALY) as improvements in fatigue are not reflected in the QALY outcomes, with no significant differences between FACETS and CLP. The strengths of this trial are its pragmatic nature and high external validity.

Trial registration:
Current Controlled Trials ISRCTN76517470.

Source: Journal of Neurology, Neurosurgery and Psychiatry - September 2, 2013 Category: Neurosurgery Authors: Thomas, S., Thomas, P. W., Kersten, P., Jones, R., Green, C., Nock, A., Slingsby, V., Smith, A. D., Baker, R., Galvin, K. T., Hillier, C. Tags: Open access, Immunology (including allergy), Multiple sclerosis Source Type: research