Growing teratoma syndrome of mediastinal nonseminomatous germ cell tumor

Nguk Chai Diong, Benedict Dharmaraj, Cindy Thomas Joseph, Narasimman SathiamurthyAnnals of Thoracic Medicine 2020 15(1):38-40Mediastinal nonseminomatous germ cell tumor (NSGCT) is rare. NSGCT shows excellent response to cisplatin-based chemotherapy. However, some tumors continue to enlarge despite normal tumor markers after chemotherapy, a rare condition called growing teratoma syndrome (GTS). Recognition of this condition is imperative for prompt surgical resection to prevent further cardiopulmonary compression and to improve survival. Multidisciplinary team meeting is important for perioperative preparation and care to improve the outcome of this high-risk surgery. Here, we report two cases of mediastinal GTS and underwent surgical resection, of which one died of pericardial decompression syndrome and the other is well.

Source: Annals of Thoracic Medicine - January 1, 2020 Category: Respiratory Medicine Authors: Nguk Chai Diong Benedict Dharmaraj Cindy Thomas Joseph Narasimman Sathiamurthy Source Type: research