Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment.

DISCUSSION: Gd does not accumulate in brains of older individuals with a BBB breakdown in the hippocampus. Thus, Gd agents can be used without risk of brain retention within a ∼2-year follow-up to study BBB in the aging human brain in relation to cognition and/or other pathologies. PMID: 31862169 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31862169?dopt=Abstract

Source: The Journal of Alzheimers Association - December 23, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research