Leukoaraiosis and Increased Cerebral Susceptibility to Ischemia: Lack of Confounding by Carotid Disease [Stroke]

Conclusions The association with more severe ischemic events (stroke versus TIA) and infarction on imaging is consistent with leukoaraiosis being a marker of increased cerebral susceptibility to ischemia. In contrast, the presence, severity of, and risk factors for atheromatous disease showed no association with leukoaraiosis, suggesting that these are two unrelated disease processes.

http://jaha.ahajournals.org/cgi/content/short/2/4/e000261?rss=1

Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: Schulz, U. G., Gruter, B. E., Briley, D., Rothwell, P. M. Tags: Stroke Source Type: research