Genetic polymorphism patterns suggest a genetic driven inflammatory response as pathogenesis in appendicitis

ConclusionsThe association of gene variants on risk of appendicitis and its severity suggest an etiologic role of genetically regulated inflammatory response. This may have implications for understanding the prognosis of untreated appendicitis as a possible self-limiting disorder and for understanding the inverse association of appendicitis with ulcerative colitis.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research