Major aphthous ulcerations associated with sickle cell anemia exacerbated by orthodontic treatment

An 18-year-old white woman was referred to our service with complaint of “ulcerations on the tongue.” The lesions worsened in the last 6 months when the orthodontic appliance was placed. The patient was vegetarian, and she reported a prolonged menstrual period. Oral examination revealed multiple symptomatic ulcerations with irregular shape with pseudomembrane involvi ng the lower lip, tongue, and buccal mucosa bilaterally. Laboratory tests were requested, which showed sickle cell trait of anemia with presence of microcytic red blood cells as well as iron deficiency and ferritin.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - December 15, 2019 Category: ENT & OMF Authors: FLAVIO LUCENA ANTUNES, PAULO EDUARDO ALENCAR DE SOUZA, GIOVANNA RIBEIRO SOUTO, HELENICE DE ANDRADE MARIGO GRANDINETTI, MARTINHO CAMPOLINA REBELLO HORTA, SORAYA DE MATTOS CAMARGO GROSSMANN Source Type: research