Fenretinide-induced Apoptosis of Acute Myeloid Leukemia Cells via NR4A1 Translocation into Mitochondria and Bcl-2 Transformation
CONCLUSIONS: Fenretinide exerts an obvious effect on AML cells both in vitro and in vivo. Besides, the NR4A1-mediated signaling pathway is highly involved in the fenretinide-induced apoptosis of AML cells.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Jie Xiong, Xingyi Kuang, Tingting Lu, Xu Liu, Bingqing Cheng, Weili Wang, Danna Wei, Xinyao Li, Zhaoyuan Zhang, Qin Fang, Depei Wu, Jishi Wang Tags: Research Paper Source Type: research
More News: Acute Leukemia | Acute Myeloid Leukemia | Cancer | Cancer & Oncology | Leukemia | Mitochondria | Study | Translocation