Sedation with midazolam worsens the diaphragm function than dexmedetomidine and propofol during mechanical ventilation in rats.

CONCLUSIONS: Twelve hours of mechanical ventilation during midazolam sedation led to a more severe diaphragm dysfunction than dexmedetomidine and propofol, possibly caused by its relative weaker antioxidant capacity. PMID: 31810122 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31810122?dopt=Abstract

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 9, 2019 Category: Drugs & Pharmacology Authors: Li SP, Zhou XL, Zhao Y Tags: Biomed Pharmacother Source Type: research