Probe Cocktail to Assess Transporter Function in Sandwich-Cultured Human Hepatocytes.
CONCLUSIONS: These data suggest that rosuvastatin and metformin can be administered as a cocktail to evaluate the function of OATP1B1, OATP1B3, BCRP, and OCT1 in SCHH, and that digoxin may not be an ideal component of such a cocktail.
PMID: 31804919 [PubMed - in process]
Source: J Pharm Pharm Sci - Category: Drugs & Pharmacology Authors: Guo C, Brouwer KLR, Brouwer KR, Stewart PW, Mosley C Tags: J Pharm Pharm Sci Source Type: research
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