Engineering of an Iranian Bordetella pertussis strain producing inactive pertussis toxin.
Conclusion. A B. pertussis of the predominant genomic and virulence lineage in Iran was successfully engineered to produce inactive PTX. This attenuated strain will be useful to further studies to develop both whole cell and acellular pertussis vaccines.
PMID: 31778110 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Nikbin VS, Keramati M, Noofeli M, Tayebzadeh F, Kahali B, Shahcheraghi F Tags: J Med Microbiol Source Type: research
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