Antituberculosis drug- induced hepatitis, an unpredictable phenotype

Conclusion: Antituberculosis drug-induced hepatotoxicity is a complex phenotype, for which age, female gender and variants of NAT2 and ABCB11 genes, have a modest contribution. Moreover, different risk factors determine susceptibility to mild and severe liver damage.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: da Silva Alcobia, M. C., M Nogueira, L., Oliveiros, B., Robalo Cordeiro, C., C Silva, H. Tags: Tuberculosis Source Type: research