MYMD-1, a novel alkaloid compound, ameliorates the course of experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is an autoimmune disease that remains in need of effective therapies. Plant-derived medicines have appealing properties for the treatment of autoimmune diseases. MYMD-1 is a synthetic plant alkaloid that has been shown to ameliorate the course of autoimmune thyroiditis. The goal of the present study was to determine whether MYMD-1 would produce similar beneficial effects in a mouse model of MS, experimental autoimmune encephalomyelitis (EAE) induced by immunization with myelin oligodendrocyte glycoprotein.
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Justin D. Glenn, Itzy Morales Pantoja, Patrizio Caturegli, Katharine A. Whartenby Tags: Short communication Source Type: research
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