Dexmedetomidine for Improved Quality of Emergence From General Anesthesia: A Dose-Finding Study.

CONCLUSIONS: D 1 at the end of surgery provides the best quality of emergence from general anesthesia including the control of cough, agitation, hypertension, tachycardia, and shivering. D 0.5 also controls emergence phenomena but is less effective in controlling cough. The 3 doses do not delay extubation. However, they cause dose-dependent hypotension. PMID: 31743169 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31743169?dopt=Abstract

Source: Anesthesia and Analgesia - November 20, 2019 Category: Anesthesiology Authors: Aouad MT, Zeeni C, Al Nawwar R, Siddik-Sayyid SM, Barakat HB, Elias S, Yazbeck Karam VG Tags: Anesth Analg Source Type: research