Determinants of Improvement of Mid-term Ejection Fraction in Patients with Acute Myocardial Infarction.

Determinants of Improvement of Mid-term Ejection Fraction in Patients with Acute Myocardial Infarction. Int Heart J. 2019 Nov 15;: Authors: Ohashi J, Sakakura K, Yamamoto K, Taniguchi Y, Tsukui T, Seguchi M, Nanba-Sato H, Shibata K, Sasaki W, Ikeda T, Wada H, Momomura SI, Fujita H Abstract Persistent severe left ventricular (LV) systolic dysfunction after acute myocardial infarction (AMI) is associated with increased morbidity and mortality, whereas mid-term recovery of LV systolic function after AMI is associated with better long-term outcomes. The purpose of this study was to investigate the determinants of mid-term improvement of LV ejection fraction (EF) in AMI patients. We included 210 AMI patients who had modified Simpson EF both at the index admission and mid-term follow up. The difference of EF between the index admission and mid-term follow-up was calculated in all study patients. The EF improvement group was defined as mid-term ≥ 10% EF increase compared with the index admission EF. Of 210 AMI patients, 46 (21.9%) were allocated to the EF improvement group and 164 (78.1%) to the non-EF improvement group. Brain natriuretic peptide (BNP) at the timing of admission was significantly greater in the EF improvement group (735.8 ± 1077.6 pg/mL) than in the non-EF improvement group (239.0 ± 419.8 pg/mL) (P
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research

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