Multicenter study of levodopa carbidopa intestinal gel in Parkinson's disease: the Turkish experince.
CONCLUSION: As it is detected by a survey performed by telephone calls with good interrater reliability, patients with PD gets better with LCIG treatment in many aspects of the disease. PMID: 31731332 [PubMed - as supplied by publisher]
CONCLUSIONS: CNB and SSNB have similar effects on pain relief, complications and functional recovery in patients receiving TKA. The optimal analgesic regimen for patients after TKA needs further identification. PMID: 31808660 [PubMed - as supplied by publisher]
CONCLUSIONS: Intraoperative acupuncture at HT7 and ear Shen Men did not reduce PAED scores after myringotomy tube placement. Based on these data, it is therefore unlikely that alarger study of the same design would demonstrate a significant effect of intraoperative acupuncture on emergence delirium after brief sevoflurane anesthesia. However, other acupuncture points or techniques could be considered. PMID: 31808657 [PubMed - as supplied by publisher]
In conclusion, the results suggest that, because of its bioactivity including the antioxidant, antimicrobial, and enzyme inhibition properties, the D. macrolepis can be accepted as a promising and natural source for the industrial applications. The present study is the first study, in which the bioactive components and the antioxidant, antimicrobial, and enzyme inhibition properties of endemic D. macrolepis plant were determined.
Publication date: Available online 7 December 2019Source: Saudi Pharmaceutical JournalAuthor(s): Kinga OstrowskaAbstractA number of psychiatric disorders, including anxiety, schizophrenia, Parkinson’s disease, depression and others CNS diseases are known to induce defects in the function of neural pathways sustained by the neurotransmitters, like dopamine and serotonin. N-arylpiperazine moiety is important for CNS-activity, particularly for serotonergic and dopaminergic activity. In the scientific literature there are many examples of coumarin-piperazine derivatives, particularly with arylpiperazines linked to a coum...
ConclusionABCB1 C3435T and ABCG2 C421A might represent a potential risk factor for breast cancer for Turkish women.
Functional coupling of M1 muscarinic acetylcholine receptor to Gαq/11 in dorsolateral prefrontal cortex from patients with psychiatric disorders: a postmortem study. Eur Arch Psychiatry Clin Neurosci. 2019 Dec 05;: Authors: Odagaki Y, Kinoshita M, Meana JJ, Callado LF, García-Sevilla JA Abstract Accumulating studies have implicated intracellular signaling through muscarinic acetylcholine receptors (mAChRs) in psychiatric illness. In the present study, carbamylcholine chloride (carbachol)-induced Gαi/o and Gαq/11 activation was identified in postmortem human prefrontal cortical ...
CONCLUSIONS: Prenatally initiated CBT did not improve maternal symptoms or child outcomes among non-help-seeking women with antenatal depression or anxiety. Our findings are not in line with present recommendations for universal screening and treatment for antenatal depression or anxiety, and future work may include the relevance of baseline help-seeking. PMID: 31806071 [PubMed - as supplied by publisher]
We present the case of a 4-year-old child who was admitted owing to the complaint of recurrent pancreatitis and had not previously been diagnosed with having metabolic disease. During inpatient treatment for acute pancreatitis, convulsions occurred with concomitant hyperammonemia, metabolic acidosis, coagulopathy, and shock 1 week after the administration of total parenteral nutrition. He was diagnosed to have PA after a metabolic work-up and confirmed to have novel mutation by molecular genetic analysis. Because children with PA may have acute pancreatitis, although rare, vomiting and abdominal pain should raise a suspici...
Conclusions The sincalide and EP cholecystagogues did not lead to significantly different HBS findings for similar patient populations or postcholecystectomy outcomes.
Physician burnout can be a contributing factor to depression, substance abuse, problems with relationships, and thoughts of suicide. Burnout of physicians also results in decreased quality, safety, and outcomes for patients and more financial costs for health-care institutions. It is not enough for health-care systems to focus on helping the individual; these organizations also need to understand that they are the main cause of physician burnout and take appropriate action to reform their processes.