Utility of Copy Number Variants in the Classification of Intracranial Ependymoma
Ependymomas are neuroepithelial tumors that differentiate along the ependymal cell lineage, a lining of the ventricles of the brain and the central canal of the spinal cord. They represent ∼1% of primary CNS tumors in adults, but ∼9% of brain tumors in children [1, 2]. The standard treatment regimen consists of surgical resection and/or adjuvant radiotherapy. No targeted chemotherapies have been devised, and tumor classification and grading remain challenging, even in the genomic era [3].
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Michael Evenson, Chunyu Cai, Vishwanathan Hucthagowder, Samantha McNulty, Julie Neidich, Shashikant Kulkarni, Sonika Dahiya Source Type: research
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