Urinary biomarkers profiles in patients with neurogenic detrusor overactivity according to their neurological condition

ConclusionAll NDO may not be created equal from the molecular standpoint. Multiple sclerosis patients had higher urinary levels of neurotrophins than in other neurologic populations with NDO. Urinary TGF β-1, a strong determinant of extracellular matrix, was significantly higher in spina bifida patients compared to SCI patients. These findings underscore the importance of using and interpreting those possible urinary markers in a disease-specific fashion.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research