Chromatin accessibility and transcription dynamics during in vitro astrocyte differentiation of Huntington ’s Disease Monkey pluripotent stem cells

Huntington ’s Disease (HD) is a fatal neurodegenerative disorder caused by a CAG repeat expansion, resulting in a mutant huntingtin protein. While it is now clear that astrocytes are affected by HD and signific...

Source: Epigenetics and Chromatin - November 13, 2019 Category: Genetics & Stem Cells Authors: Alexandra V. Goodnight, Isaac Kremsky, Sujittra Khampang, Yoon Hee Jung, James M. Billingsley, Steven E. Bosinger, Victor G. Corces and Anthony W. S. Chan Tags: Research Source Type: research