Efficacy of a single dose of dexmedetomidine for cough suppression during anesthetic emergence: a randomized controlled trial

Conclusion Compared with an infusion of low-dose remifentanil alone, the addition of a single dose (0.5 μg·kg−1) of dexmedetomidine during emergence from sevoflurane-remifentanil anesthesia was effective in attenuating coughing and hemodynamic changes and did not exacerbate respiratory depression after thyroid surgery. This trial was registered at Clinicaltrial.gov, identifier: NCT01774305.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research