Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide

ConclusionsDifferential changes are found in astrocyte and microglia genes in PFC subregions in relation to schizophrenia and suicide, indicating possible disturbances of glia homeostasis in these conditions.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research

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In today’s show, Gabe talks with Robert Kolker, author of the New York Times bestselling — and Oprah’s book club pick — book Hidden Valley Road. This non-fiction biography is the true story of a mid-century American family besieged by schizophrenia. Of their 12 children, 6 struggled with the severe mental disorder.  Join us for the incredible story of the family who became science’s greatest hope in the quest to understand schizophrenia. SUBSCRIBE &REVIEW   Guest information for ‘Robert Kolker- Large Family Schizophrenia’ Podcast Episode Robert Kolker is the...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Family General Interview Schizophrenia The Psych Central Show Source Type: blogs
Authors: Edinoff A, Ruoff MT, Ghaffar YT, Rezayev A, Jani D, Kaye AM, Cornett EM, Kaye AD, Viswanath O, Urits I Abstract Purpose of Review: Antipsychotics are the standard of care when it comes to the treatment of Schizophrenia, and they are often used in Bipolar as well. Their use can come with adverse effects such as extrapyramidal movements, metabolic complications as well as cardiovascular complications such as a prolonged QT interval. Treatment for these side effects ranges from the treatment of the complications up to the cessation of the medication, which could come at the expense of the user's stability. Bo...
Source: Psychopharmacology Bulletin - Category: Psychiatry & Psychology Tags: Psychopharmacol Bull Source Type: research
Who do you think understands more about bipolar disorder: a psychiatrist or a patient with the illness? In this Not Crazy podcast, we discuss whether a patient can be considered a mental health expert without all the credentials after their name. Today we invite writer and bipolar advocate Natasha Tracy — who also has bipolar disorder — to the show to give her opinion. Would you seek advice from a patient? Join us for an in-depth discussion on mental health patients as experts. (Transcript Available Below) Subscribe to Our Show! And Please Remember to Rate &Review Us!   Guest Information for &lsquo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Not Crazy Podcast Policy and Advocacy Source Type: blogs
Who do you think understands more about bipolar disorder: a psychiatrist or a patient with the illness? In this Not Crazy podcast, we discuss whether a patient can be considered a mental health expert without all the credentials after their name. Today we invite writer and bipolar advocate Natasha Tracy — who also has bipolar disorder — to the show to give her opinion. Would you seek advice from a patient? Join us for an in-depth discussion on mental health patients as experts. (Transcript Available Below) Subscribe to Our Show! And Please Remember to Rate &Review Us!   Guest Information for &lsquo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Not Crazy Podcast Policy and Advocacy Source Type: blogs
Although suicide risk is relevant in First Episode Schizophrenia (FES), little data are reported on suicidal ideation and its longitudinal stability. Aim of this study was: (1) to evaluate incidence rates of suicide attempts, completed suicide and suicidal...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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Source: Archives of Suicide Research - Category: Psychiatry & Psychology Authors: Source Type: research
CONCLUSION: First-episode schizophrenia patients with suicide attempts had more severely impaired neurocognitive performances in specific domains. Fundamental neurocognitive dysfunctions should be assessed, detected, and treated after their suicide risk assessments. PMID: 32949038 [PubMed - as supplied by publisher]
Source: Suicide and Life-Threatening Behavior - Category: Psychiatry & Psychology Authors: Tags: Suicide Life Threat Behav Source Type: research
It is well known that only a small proportion of the human genome code for proteins; the rest belong to the family of RNAs that do not code for protein and are known as non-coding RNAs (ncRNAs). ncRNAs are further divided into two subclasses based on size: 1) long non-coding RNAs (lncRNAs;>200 nucleotides) and 2) small RNAs (
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
AbstractEmergency psychiatry has the main role of resolving suicidal behavior and aggression. These severe psychiatric symptoms can be found in many psychiatric disorders such as schizophrenia, bipolar disorder, major depression, personality disorders, cognitive disorders, intellectual disability and substance abuse. Although indications for the use of antipsychotics are limited to a specific group of diseases, they are frequently used as rescue medication in high-risk or nonresponsive cases. Clozapine, the gold standard for TRS (treatment resistant schizophrenia) is effective in controlling aggression. The aim of the rese...
Source: Psychiatric Quarterly - Category: Psychiatry Source Type: research
BACKGROUND: Patients with schizophrenia are at a higher risk for suicide compared with the general population. Dopamine beta-hydroxylase (D βH) plays a key role in the conversion of dopamine to norepinephrine, which is related to suicidal behavior and cogn...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
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