Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide

ConclusionsDifferential changes are found in astrocyte and microglia genes in PFC subregions in relation to schizophrenia and suicide, indicating possible disturbances of glia homeostasis in these conditions.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research

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Conclusion: Our results demonstrated that a significant percentage of patients affected by both mood disorders and schizophrenia shows relevant social dysfunction. Social dysfunction is related, but not completely explained by psychopathological severity. In several patients, it tends to persist also during remission state. Socio-demographic and lifestyle factors were also found to play a role and should therefore be taken into consideration in further studies investigating social dysfunction.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
ConclusionsRumination is known to be associated with poor prognosis in mental health. This study suggests that rumination is a maladaptive coping style associated not only with worry, distress and illness severity, but also with socioeconomic status. Also, rumination demonstrated a specific association with panic disorder.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Almost half (48%) of children and adolescents with a psychotic disorder said they recently had suicidal thoughts or had in the past considered death by suicide when interviewed in the emergency department (ED) using a brief screening questionnaire, according to areport published this week inPsychiatric Services. Most of these youth did not report a chief complaint related to suicidal ideation or behavior when arriving at the ED.Notably, half of the children and adolescents who screened positive for suicide using the Ask Suicide-Screening Questions (ASQ) screen were discharged from the ED, including 44% of those who reporte...
Source: Psychiatr News - Category: Psychiatry Tags: Ask Suicide-Screening Questions Jonathan DeVylder Psychiatric Services psychotic disorders youth Source Type: research
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.The group of international experts, which also includes scientists from the National Institutes of Health, Stanford University, Harvard Medical School, Columbia University Medical Center and University College London, point to inflammation-related diseases as the cause of 50 percent of all deaths worldwide.Inflammation is a naturally occurring response by the body ’s immune system that helps fight illness and infection. Whe...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
(Natural News) After his pet cat scratched him, a teenage boy developed a bacterial infection that caused rapid-onset schizophrenia. Experts diagnosed the patient with “cat-scratch disease.” The anonymous boy became severely suicidal and paranoid about his pets. He ended up at the hospital four times in 18 months. As his mental condition worsened, he experienced hallucinations,...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
BACKGROUND: Schizophrenia is associated with a high rate of suicide. AIM: Our study was aimed to identify the rates of suicide ideas in patients with schizophrenia as well as the risk factors associated with suicide ideas. METHODS: As many ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
One thing I shared with my wife Rachel about a year into our relationship was the time I suffered a nervous breakdown in graduate school. It would be an important moment in any relationship because I shared the time in my life when I was most vulnerable and at my weakest point. Did I technically suffer a nervous breakdown? I’m not sure, all I remember is the turning point came when I drove home late one night, collapsed on my kitchen floor and started crying uncontrollably. Up to that point, I had developed a quasi-schizophrenic outlook on life and could no longer bear the weight of the world-view I constructed. In p...
Source: Psych Central - Category: Psychiatry Authors: Tags: Borderline Personality Personal Stories Stigma Suicide Antidepressants Borderline Personality Disorder college Delusions Life Transition Nervous Breakdown Paranoia Psychosis Shame Stigmatization Source Type: news
This study examined the relationships between hallucinations, delusions, depression, social isolation, and suicidal ideation. Participants were involved in the cross-sectional Collaborative Psychiatric Epidemiology Surveys (CPES) including a large general population-based sample of households in the United States between 2001 and 2003. Participants (n  = 12,195) included adults over the age of 18 in the United States, all of whom completed a psychosis assessment. Hopelessness was measured using The Calgary Depression Scale for Schizophrenia (CDSS), hallucinations and delusions by the Positive and Negative Syn...
Source: Clinical Social Work Journal - Category: Psychiatry & Psychology Source Type: research
We all have an idea in our heads of what a mass shooter looks like. But how accurate is it? Does anyone actually know? Who would you trust to find out? Is there any data on this? Well, now there is. The National Council on Behavioral Health has recently completed a comprehensive report, “Mass Violence in America: Causes, Impacts, and Solutions.” Listen in as our host interviews the medical director of the National Council for an in-depth explanation of what this exhaustive document has revealed. SUBSCRIBE &REVIEW Guest information for ‘National Council on Behavioral Health’ Podcast Episode D...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anger Brain and Behavior Interview Mental Health and Wellness Podcast Policy and Advocacy Psychiatry Psychology Research The Psych Central Show Violence and Aggression Source Type: blogs
BACKGROUND: Patients with schizophrenia (SCZ) run a lifelong risk of suicide. Alterations in glia activities in the prefrontal cortex (PFC) have been reported in relation to suicide in patients with SCZ. While immune processes in the CNS have been related ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
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