Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70 TM a human monoclonal autoantibody to the TSH receptor with TSH antagonist activity

ConclusionsThe toxicology, pharmacodynamic and pharmacokinetic data in this preclinical study were helpful in designing the first in human study with K1-70 ™ administered to subjects with Graves’ disease.
Source: Autoimmunity Highlights - Category: Allergy & Immunology Source Type: research