Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 AND GST

ConclusionPatients with theCYP2E1 variant genotype or Null GSTT1 showed higher risk of presenting DILI (p = 0.09; OR: 4.57; 95% CI: 0.75–27.6). Individuals with both genotypes had no increased risk compared to individuals with one genotype.
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research