High prevalence of CTX-M-1 group in ESBL-producing enterobacteriaceae infection in intensive care units in southern Chile
Publication date: Available online 24 April 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Monica Pavez, Claudia Troncoso, Irma Osses, Rodrigo Salazar, Vijna Illesca, Patricia Reydet, Claudio Rodriguez, Carolina Chain, Carla Concha, Leticia BarrientosAbstractEnterobacteria-producing extended-spectrum β-lactamases (ESBL) play an important role in healthcare infections, increasing hospitalization time, morbidity and mortality rates. Among several ESBLs that emerge from these pathogens, CTX-M-type enzymes had the most successful global spread in different epidemiological settings. Latin America presen...
Source: The Brazilian Journal of Infectious Diseases - April 24, 2019 Category: Infectious Diseases Source Type: research

Editorial
Publication date: January–February 2019Source: The Brazilian Journal of Infectious Diseases, Volume 23, Issue 1Author(s): Luciano Z. Goldani (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - April 18, 2019 Category: Infectious Diseases Source Type: research

Epidemiology and clinical characteristics of herpes zoster in a tertiary care hospital in Brazil
ConclusionThe results of this study demonstrate a high burden of HZ disease in a Brazilian tertiary care hospital in the HZ vaccination era. Awareness of the incidence and comorbidity factors associated with HZ in Latin American countries such as Brazil contribute for adoption and implementation of strategies for immunization in this area. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 31, 2019 Category: Infectious Diseases Source Type: research

A systematic review on the influence of hla-b polymorphisms on hiv-1 mother-to-child-transmission
ConclusionHLA-B*57 group allele can be protective against MTCT while HLA-B*35 groups alleles are consistently associated with HIV-1 MTCT. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 27, 2019 Category: Infectious Diseases Source Type: research

Evaluation of the cervicovaginal environment in asymptomatic Human T-cell lymphotropic virus type 1 infected women
This study aimed to assess the cytokine profile and cytopathological findings in the cervicovaginal fluid of asymptomatic HTLV-1-infected women.MethodsHTLV-1-infected and uninfected women were selected at the Centro de Atendimento ao Portador de HTLV in Salvador-Brazil. None of the included HTLV-1-infected women reported any HTLV-1-associated diseases. All volunteers underwent gynecological examination to collect cervicovaginal fluid. Cytokine quantification was performed using the Cytometric Bead Array (CBA) Human Th1/Th2/Th17 kit. Light microscopy was used to evaluate cervicovaginal cytopathology. In addition, proviral l...
Source: The Brazilian Journal of Infectious Diseases - March 19, 2019 Category: Infectious Diseases Source Type: research

The first outbreak of measles virus caused by imported genotype D8 in Jiangsu province of China
Publication date: Available online 12 March 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Xiuying Deng, Ying Hu, Peishan Lu, Ming-hao Zhou, Hongxiong GuoAbstractHere we reported the outbreak of measles cases caused by the genotype D8 measles virus (MeV) for the first time in Jiangsu province in China, which was possibly imported by a foreign student from Laos. Throat swab specimens were collected, and used to isolate virus. 634-bp fragment of the N gene and 1854-bp fragment of H gene were amplified by reverse transcription-PCR and sequenced, respectively. Phylogenetic results indicated that they belong...
Source: The Brazilian Journal of Infectious Diseases - March 13, 2019 Category: Infectious Diseases Source Type: research

How are HCV-infected patients being identified in Brazil: a multicenter study
ConclusionsThis multicenter Brazilian study showed that the mean time to reach a referral center for treatment was almost two years. Primary care physicians diagnoses most hepatitis C cases in the country. Population campaigns and medical education should be encouraged to intensify screening of asymptomatic individuals, considering the efficiency of check-ups in identifying new patients. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 7, 2019 Category: Infectious Diseases Source Type: research

Evaluation of the cervicovaginal environment in asymptomatic HTLV-1 infected women
This study aimed to assess the cytokine profile and cytopathological findings in the cervicovaginal fluid of asymptomatic HTLV-1-infected women.MethodsHTLV-1-infected and uninfected women were selected at the Centro de Atendimento ao Portador de HTLV in Salvador-Brazil. None of the included HTLV-1-infected women reported any HTLV-1-associated diseases. All volunteers underwent gynecological examination to collect cervicovaginal fluid. Cytokine quantification was performed using the Cytometric Bead Array (CBA) Human Th1/Th2/Th17 kit. Light microscopy was used to evaluate cervicovaginal cytopathology. In addition, proviral l...
Source: The Brazilian Journal of Infectious Diseases - March 7, 2019 Category: Infectious Diseases Source Type: research

Staphylococcus aureus in tonsils of patients with recurrent tonsillitis: prevalence, susceptibility profile, and genotypic characterization
ConclusionsMDR isolates colonizing tonsils even without infection, demonstrate persistence of the bacterium and possibility of antimicrobial resistance dissemination and recurrence of infection. A specific clone in patients colonized by S. aureus was not demonstrated. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 7, 2019 Category: Infectious Diseases Source Type: research

Previous hepatitis E virus infection, cirrhosis and insulin resistance in patients with chronic hepatitis C
ConclusionPatients with chronic hepatitis C are under risk of hepatitis E virus superinfection in Brazil. The trend toward association between cirrhosis and previous HEV infection suggests that it may accelerate liver fibrosis in patients with chronic hepatitis C. In addition, previous infection by HEV is independently associated with insulin resistance in the studied population, which may be an extra-hepatic manifestation of hepatitis E that persists after resolution of the active infection, and may contribute to fibrosis progression. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 4, 2019 Category: Infectious Diseases Source Type: research

Hepatitis E virus prevalence in Egyptian children with transfusion-dependent thalassemia
ConclusionsThalasemic patients are vulnerable to chronicity and increased risk of morbidity and mortality from HEV infection. Frequent assessment of liver enzymes in thalassemic patients to monitor subclinical HEV is recommended. Close monitoring and HEV screening of blood donations should be taken in consideration. Public awareness about HEV endemicity, modes of transmission, and risk hazards especially in high risk group should be done to reduce the disease burden. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - March 1, 2019 Category: Infectious Diseases Source Type: research

Polyomaviruses BK and JC DNA infection in peripheral blood cells from blood donors
DiscussionOur study provides important data on polyomavirus infection in peripheral blood mononuclear leukocytes in immunocompetent individuals. These data indicate significant differences between the prevalence of BKV and JCV infection in healthy blood donors. The prevalence of BK and JC virus infection is higher in the age range 30–39 years compared to other age ranges. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - February 25, 2019 Category: Infectious Diseases Source Type: research

Effects of sub-minimum inhibitory concentrations of ciprofloxacin on biofilm formation and virulence factors of Escherichia coli
Publication date: Available online 21 February 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Guofeng Dong, Jiahui Li, Lijiang Chen, Wenzi Bi, Xiaoxiao Zhang, Haiyang Liu, Xiaoyang Zhi, Tieli Zhou, Jianming CaoAbstractObjectiveTo evaluate the influence of sub-minimum inhibitory concentrations (MICs) of ciprofloxacin (CIP) on biofilm formation and virulence factors of Escherichia coli clinical isolates.MethodsSub-MICs of CIP were determined using growth curve experiments. The biofilm-forming capacity of E. coli clinical isolates and E. coli ATCC 25922 treated or untreated with sub-MICs of CIP was assesse...
Source: The Brazilian Journal of Infectious Diseases - February 22, 2019 Category: Infectious Diseases Source Type: research

Early use of polymyxin B reduces the mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection
Publication date: Available online 21 February 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Qiqiang Liang, Man Huang, Zhijiang XuAbstractPolymyxin B is one of the last resort option for carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection in China. Therefore, the timing of administration of polymyxin is frequently delayed. We collected 40 cases of CRKP bloodstream infections (BSIs) treated with combinations based on polymyxin B over 30 months. The primary outcome, 30-day mortality rate, was 52.5% (21/40). Early administration of polymyxin B is meant to administer the drug within 48&...
Source: The Brazilian Journal of Infectious Diseases - February 22, 2019 Category: Infectious Diseases Source Type: research

HLA-B*14 allele predicts HIV-1 mother-to-child-transmission, in Salvador, Brazil
ConclusionHLA-B*57 group allele can be protective against MTCT while HLA-B*35 groups alleles are consistently associated with HIV-1 MTCT. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - February 15, 2019 Category: Infectious Diseases Source Type: research

Acknowledgements 2018
Publication date: November–December 2018Source: The Brazilian Journal of Infectious Diseases, Volume 22, Issue 6Author(s): (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - February 13, 2019 Category: Infectious Diseases Source Type: research

HIV testing and HIV knowledge among men who have sex with men in Natal, Northeast Brazil
ConclusionsThe frequency of HIV testing among MSM from Natal is rather low, especially in younger MSM, and knowledge about HIV transmission is inappropriate. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - February 11, 2019 Category: Infectious Diseases Source Type: research

Human T cell lymphotropic virus type 1 infection among men who have sex with men in Central Brazil
Publication date: Available online 6 December 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Lisie Souza Castro, Grazielli Rocha de Rezende, Fernanda Rodas Pires Fernandes, Larissa Melo Bandeira, Marco Antonio Moreira Puga, Tayana Serpa Ortiz Tanaka, Sabrina Moreira dos Santos Weis-Torres, Ana Carolina Paulo Vicente, Koko Otsuki, Ana Rita Coimbra Motta-CastroAbstractHuman T cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus discovered in humans and is endemic in several parts of the world. Because of risk behaviors, mainly sexual, men who have sex with men (MSM) are at high risk of acquiri...
Source: The Brazilian Journal of Infectious Diseases - January 17, 2019 Category: Infectious Diseases Source Type: research

Chronic skull osteomyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient
We report the case of an HIV-infected patient with history of recurring itching on his scalp and repetitive local trauma. For eighteen months, he noticed a painful and slow growing lump on his scalp. He was submitted to an excisional biopsy of the lesion but no etiological diagnosis was identified. After this procedure, the post-surgical wound never completely healed. At admission, the patient presented nausea and headache for three days and an open orifice into his skull. Investigations confirmed meningitis and skull osteomyelitis caused by Cryptococcus neoformans. He was treated with bone debridement and combined systemi...
Source: The Brazilian Journal of Infectious Diseases - January 5, 2019 Category: Infectious Diseases Source Type: research

Molecular characteristics and virulence gene profiles of Staphylococcus aureus causing bloodstream infection
ConclusionST5-t2460 was the most common clone in S. aureus causing bloodstream infection followed by ST188-t189, which had never been noted in China before. Moreover, ST5-t2460 harbored more virulence genes than ST188-t189, and the prevalence of ST239 clone decreased with the proportion of MRSA among all S. aureus isolates. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 28, 2018 Category: Infectious Diseases Source Type: research

Novel fluoronucleoside analog NCC inhibits lamivudine-resistant hepatitis B virus in a hepatocyte model
In conclusion, screening for antiviral compounds active against lamivudine-resistant HBV can be carried out with relative ease using hepG2.RL1 cells. NCC is a potential antiviral agent against wild-type HBV and clinical lamivudine-resistant HBV and deserves evaluation for the treatment of HBV infection. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 24, 2018 Category: Infectious Diseases Source Type: research

Measles outbreak in Brazil, 2018
Publication date: September–October 2018Source: The Brazilian Journal of Infectious Diseases, Volume 22, Issue 5Author(s): Luciano Z. Goldani (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 7, 2018 Category: Infectious Diseases Source Type: research

Chronic skull ostemyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient
Publication date: Available online 6 December 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Natanael Sutikno Adiwardana, Juliana de Angelo Morás, Leandro Lombo Bernardo, Giselle Burlamaqui Klautau, Wladimir Queiroz, Jose Ernesto Vidal (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 7, 2018 Category: Infectious Diseases Source Type: research

Epidemiology of pathogens causing urinary tract infections in an urban community in southern Brazil
Publication date: Available online 5 December 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Carlos E. Reu, Waldemar Volanski, Karoline C. Prediger, Geraldo Picheth, Cyntia M.T. Fadel-PichethAbstractThe frequency of urinary tract infection (UTI) and uropathogens in the community was determined by assessing urine culture results of outpatients at a Brazilian public laboratory in a year period. Patients were classified according to sex and age; women were additionally classified considering pregnancy or diabetes. Cultures were considered positive when growing pure cultures with colony counts>104 C...
Source: The Brazilian Journal of Infectious Diseases - December 6, 2018 Category: Infectious Diseases Source Type: research

Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis
In this study, we screened 87 overlapping synthetic peptides encoded by five RD2 proteins for diagnosing tuberculosis epitopes in 50 active tuberculosis (TB) cases, 31 non-tuberculosis patients and 36 healthy individuals. A pool of promising epitopes was then assessed for their diagnostic value in 233 suspected TB patients using a whole blood IFN-γ release assay.Only 10 peptides were recognized by more than 10% of active tuberculosis patients. The IFN-γ release responses to Rv1986-P9, P15, P16, Rv1988-P4, P11, and Rv1987-P11 were significantly higher in the active TB group than in the control groups (p 
Source: The Brazilian Journal of Infectious Diseases - December 6, 2018 Category: Infectious Diseases Source Type: research

HTLV-1 infection among men who have sex with men in Central Brazil
Publication date: Available online 6 December 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Lisie Souza Castro, Grazielli Rocha de Rezende, Fernanda Rodas Pires Fernandes, Larissa Melo Bandeira, Marco Antonio Moreira Puga, Tayana Serpa Ortiz Tanaka, Sabrina Moreira dos Santos Weis, Ana Carolina Paulo Vicente, Koko Otsuki, Ana Rita Coimbra Motta-CastroAbstractHuman T-cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus discovered in humans and is endemic in several parts of the world. Because of risk behaviors, mainly sexual, men who have sex with men (MSM) are at high risk of acquiring HTLV...
Source: The Brazilian Journal of Infectious Diseases - December 6, 2018 Category: Infectious Diseases Source Type: research

Molecular types of Cryptococcus species isolated from patients with cryptococcal meningitis in a Brazilian tertiary care hospital
Publication date: Available online 30 November 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Fernanda Wirth, Maria Isabel Azevedo, Luciano Z. GoldaniAbstractThere are limited data on the molecular epidemiology of cryptococcosis in Brazil. Here, we report on the identification of the molecular pattern of the Cryptococcus species that caused meningitis in patients admitted in a Brazilian reference tertiary care hospital, and review the published studies addressing the molecular epidemiology of Cryptococcus in Brazil. Our study has shown the predominance of molecular type VNII in predominantly HIV-infecte...
Source: The Brazilian Journal of Infectious Diseases - December 1, 2018 Category: Infectious Diseases Source Type: research

Clinical management of leprosy patients during the yellow fever outbreak in Brazil
Publication date: Available online 27 November 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Rachel Gimenes Albuquerque, Jane Tomimori, Lucile Maria Floeter-Winter, Sergio Tufik, Monica Levy Andersen (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 28, 2018 Category: Infectious Diseases Source Type: research

Assessment of conventional PCR and real-time PCR compared to the gold standard method for screening Streptococcus agalactiae in pregnant women
In this study, we aimed to compare the performance of conventional polymerase chain reaction (PCR) and real-time PCR (qPCR) assays as screening methods for GBS in pregnant women against the microbiological culture method considered as the gold-standard. A total of 130 samples from pregnant women were analyzed for sensitivity, specificity, positive predictive value, and negative predictive value. Statistical analysis was performed using the SPSS software, version 20.0. The verified colonization rate was 3.8% with the gold-standard, 17.7% with conventional PCR assay, and 29.2% with the qPCR test. The trials with conventional...
Source: The Brazilian Journal of Infectious Diseases - November 23, 2018 Category: Infectious Diseases Source Type: research

Time of catheter removal in candidemia and mortality
ConclusionsThe impact of CVC removal is dependent on whether the optimal analysis strategy is deployed and should be taken into consideration in future analyses. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 21, 2018 Category: Infectious Diseases Source Type: research

Monetary costs and hospital burden associated with the management of invasive fungal infections in Mexico: a multicenter study
Publication date: Available online 2 November 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): D.E. Corzo-León, D. Perales-Martínez, A. Martin-Onraet, N. Rivera-Martínez, A. Camacho-Ortiz, H. Villanueva-LozanoAbstractBackgroundInvasive fungal infections (IFIs) affect>1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. IFIs should be considered as a public-health problem and major actions should be taken to tackle them and their associated costs. Aim To report the incidence of IFIs in four Mexican hospitals, to describe the economic cost associa...
Source: The Brazilian Journal of Infectious Diseases - November 3, 2018 Category: Infectious Diseases Source Type: research

The influenza season 2016/17 in Bucharest, Romania – surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital
ConclusionsDistinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 1, 2018 Category: Infectious Diseases Source Type: research

A 19-year old man with IgA vasculitis after vaccination
Publication date: Available online 30 October 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alexandre Malek, Sara Isabel Gomez-Villegas, Alejandro de la Hoz, Cima Nowbakht, Cesar A. AriasAbstractA 19-year-old patient who mistakenly received two doses of influenza vaccine 10 days before presentation, was admitted with malaise, weakness, and a purpuric non-blanching rash most prominent on the ankles followed by abdominal pain and hematochezia 72 h later. The diagnosis of influenza vaccine-related Henoch–Schonlein vasculitis was made. This complication, although rare, is the most common vasculi...
Source: The Brazilian Journal of Infectious Diseases - October 31, 2018 Category: Infectious Diseases Source Type: research

Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center
Publication date: Available online 30 October 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Karla Maria Tamez-Torres, Pedro Torres-Gonzalez, Miguel E. Cervera-Hernandez, Barbara Chavez-Mazari, Corazon de Jesus Barrientos-Flores, Miriam Bobadilla-del Valle, Alfredo Ponce-de-Leon, Jose Sifuentes-OsornioAbstractObjectivesTo determine the factors associated with MTBC-positive blood culture.MethodsCase-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015.ResultsWe reviewed medical records of 533 patients with culture-proven TB, of whom 27.2% (145/533) had blood cult...
Source: The Brazilian Journal of Infectious Diseases - October 31, 2018 Category: Infectious Diseases Source Type: research

Is community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) an emerging pathogen among children in Brazil?
Publication date: Available online 30 October 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Rolando Paternina-de la Ossa, Seila Israel do Prado, Maria Célia Cervi, Denissani Aparecida Ferrari dos Santos Lima, Roberto Martinez, Fernando Bellissimo-RodriguesAbstractBackgroundCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is spreading worldwide, but little is known about the epidemiology of this pathogen in Brazil.ObjectiveTo evaluate clinical and microbiological features of children with S. aureus infections admitted to a university hospital.MethodsThis was a cross-sect...
Source: The Brazilian Journal of Infectious Diseases - October 31, 2018 Category: Infectious Diseases Source Type: research

Molecular detection of Mycobacterium leprae by Polymerase Chain Reaction in captive and free-ranging wild animals
Publication date: Available online 30 October 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Fernanda H. Maruyama, Thais O. Morgado, Richard C. Pacheco, Luciano Nakazato, Valeria Dutra (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - October 31, 2018 Category: Infectious Diseases Source Type: research

Antiretroviral therapy immunologic non-response in a Brazilian population: association study using pharmaco- and immunogenetic markers
Publication date: Available online 28 October 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Antonio V.C. Coelho, Ronald R. de Moura, Rafael L. Guimarães, Lucas A.C. Brandão, Sergio CrovellaAbstractObjectiveAntiretroviral therapy (ART) saved millions from HIV-1 infection and AIDS, but some patients do not experience adequate CD4+ T cells gain despite achieving viral suppression. The genetic component of this condition is not yet completely elucidated.ObjectiveTo identify predictive genetic markers of immune response to ART.MethodsCase–control study. Out of 176 HIV-infected patients r...
Source: The Brazilian Journal of Infectious Diseases - October 29, 2018 Category: Infectious Diseases Source Type: research

Viral detection profile in children with severe acute respiratory infection
ConclusionsOther viruses can be implicated in SARI in children. The role of viral codetection has not yet been completely elucidated. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - October 24, 2018 Category: Infectious Diseases Source Type: research

Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro
ConclusionPregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - October 17, 2018 Category: Infectious Diseases Source Type: research

Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces
Publication date: Available online 25 September 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Igor Vasconcelos Rocha, Danilo Elias Xavier, Karoline Rissele Henrique de Almeida, Sibele Ribeiro de Oliveira, Nilma Cintra LealAbstractAcinetobacter baumannii is one of the most frequent Gram-negative opportunistic pathogens associated with hospital-acquired infection worldwide. We briefly describe A. baumannii isolates that were recovered from surrounding ICU bed surfaces, exhibiting multidrug resistance phenotype and belonging to some widely spread clonal complexes of clinical A. baumannii isolates. (Source...
Source: The Brazilian Journal of Infectious Diseases - October 5, 2018 Category: Infectious Diseases Source Type: research

One-step real-time PCR assay for detection and quantification of RNA HCV to monitor patients under treatment in Brazil
Publication date: Available online 20 September 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Elisabete Andrade, Daniele Rocha, Marcela Fontana-Maurell, Elaine Costa, Marisa Ribeiro, Daniela Tupy de Godoy, Antonio G.P. Ferreira, Amilcar Tanuri, Patrícia Alvarez, Rodrigo BrindeiroAbstractThe Brazilian Public Health Service provides pegylated alfa-interferon (αPEG-IFN) free-of-charge to treat patients infected with HCV. The primary goal of HCV therapy is the long-term elimination of HCV from the blood to reduce the risk of HCV associated complications and death. Patient viremia affects treat...
Source: The Brazilian Journal of Infectious Diseases - September 21, 2018 Category: Infectious Diseases Source Type: research

Increasing prevalence and dissemination of invasive nontyphoidal Salmonella serotype Typhimurium with multidrug resistance in hospitalized patients from southern Brazil
ConclusionGreater public health attention should be given to prevent salmonellosis in the community and in hospital settings to reduce the rates of Typhimurium strains with multi-drug resistance. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - September 20, 2018 Category: Infectious Diseases Source Type: research

Incidence of surgical site infection after craniotomy: comparison between three months and twelve months of epidemiological surveillance
Conclusion: The incidence of SSI after craniotomy is high. Reducing the duration of the post-discharge surveillance period from 12 months to 3 months did not cause significant losses in the numbers of SSIs identified or a substantial decrease in their incidence. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - September 14, 2018 Category: Infectious Diseases Source Type: research

Differences in the replicative capacities of clinical isolates of dengue virus in C6/36 cells and in urban populations of Aedes aegypti from Colombia, South America
In this study, we evaluated the replicative capacity of strains isolated in Medellin between 2003 and 2007 in C6/36 cells and in colonies of Aedes aegypti collected during 2010–2011 from high or low-incidence areas within the same city. The phylogenetic analysis grouped isolates according to the predominant genotypes found in the Americas, and the in vitro characterization showed differences in the morphological changes induced by the isolates of each of the isolated serotypes compared to the reference serotypes. In vitro replicative capacity studies demonstrated that genomic copy number increased at four days post-i...
Source: The Brazilian Journal of Infectious Diseases - August 28, 2018 Category: Infectious Diseases Source Type: research

Clostridium difficile contamination in retail meat products in Brazil
Publication date: Available online 23 August 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Renata N. Pires, Cassia F.B. Caurio, Gabriele Z. Saldanha, Andreza F. Martins, Alessandro C. Pasqualotto (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 24, 2018 Category: Infectious Diseases Source Type: research

The impact of urinary incontinence on the quality of life and on the sexuality of patients with HAM/TSP
Conclusion: UI is common in HTLV-1 patients and may cause serious impairment in quality of life, with social, psychological and hygienic consequences. Nonetheless, there are few studies on this subject and their impact on mood and sexuality. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 24, 2018 Category: Infectious Diseases Source Type: research

Inadequate use of antibiotics and increase in neonatal sepsis caused by resistant bacteria related to health care assistance: a systematic review
ConclusionsDespite their low-quality evidence, the studies demonstrated the association between inadequate use of ATM and increase of neonatal resistant bacterial HAI in neonatal units. However, there is significant difficulty in conducting high-quality studies in this population due to ethical issues tied to randomized trials. Therefore, new studies should be encouraged to recommend adequate treatment of newborns without increasing the risk of HAI by multidrug-resistant bacteria. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 18, 2018 Category: Infectious Diseases Source Type: research

Prevalence of hepatitis C among dock workers
Publication date: Available online 16 August 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Roberto Focaccia, Adriana Silva de Moraes, Maria Luiza Alessi Ribeiro, Karla Fabiana Begosso Sampaio da Fonseca Carbonari, Bruna de Souza Quevedo (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 16, 2018 Category: Infectious Diseases Source Type: research

Secular trends of candidemia at a Brazilian tertiary care teaching hospital
Publication date: Available online 16 August 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Paula Rocha Braga, Isabela L. Cruz, Isadora Ortiz, Gloria Barreiros, Simone A. Nouér, Marcio NucciAbstractBackgroundCandidemia is the most frequent invasive fungal disease in hospitalized patients, and is associated with high mortality rates. The main objective of this study was to evaluate changes in the epidemiology of candidemia at a tertiary care hospital in a 21-year period.MethodsWe evaluated all episodes of candidemia diagnosed between 1996 and 2016 at a University-affiliated tertiary care hospital ...
Source: The Brazilian Journal of Infectious Diseases - August 16, 2018 Category: Infectious Diseases Source Type: research

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran
Publication date: Available online 13 August 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Amir Hossein Zahirnia, Ali Bordbar, Sahar Ebrahimi, Adel Spotin, Somayeh Mohammadi, Seyedeh Maryam Ghafari, Setareh Ahmadvand, Negar Jabbari, Ahmad Reza Esmaeili Rastaghi, Parviz ParviziAbstractBackgroundLeishmania major is a causative agent of zoonotic cutaneous leishmaniasis in the center of Iran, Abarkouh district. Molecular characterization and precise incrimination of Leishmania species was carried out to perform controlling measurements and to design treatment programs for zoonotic cutaneous leishmaniasis.M...
Source: The Brazilian Journal of Infectious Diseases - August 14, 2018 Category: Infectious Diseases Source Type: research