Seroprevalence of chikungunya virus infection in five hospitals within anyigba, kogi State of Nigeria
This study determined seroprevalence of active and past CHIKV infection among febrile patients who tested negative for malaria and typhoid fever. Sera from 243 febrile patients were screened for CHIKV IgG and IgM using an immunochromatographic test kit. Clinical and socio-demographic variables were collected using a structured questionnaire. Recent CHIKV infection was observed in 5.8% of the study participants while 25.1% had IgG antibodies demonstrating previous infection. Significant associations were observed between seropositivity and age of participants (p 
Source: The Brazilian Journal of Infectious Diseases - January 28, 2020 Category: Infectious Diseases Source Type: research

Thermotolerance of Histoplasma capsulatum at 40 °C predominates among clinical isolates from different Latin American regions
Publication date: Available online 25 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Jorge H. Sahaza, Gabriela Rodríguez-Arellanez, Cristina E. Canteros, María del Rocío Reyes-Montes, Maria Lucia TaylorAbstractThe yeast phase of 22 Histoplasma capsulatum clinical isolates from Mexico, Argentina, Colombia, and Guatemala and three reference strains, one from Panama and two from the United States of America (USA), were screened for thermosensitivity characteristics using different analyses. Growth curves at 0, 3, 6, 12, 24, and 30 h of incubation at 37 and 40 °C, the gr...
Source: The Brazilian Journal of Infectious Diseases - January 25, 2020 Category: Infectious Diseases Source Type: research

Diagnostic parameters and reliability of four rapid immunochromatographic tests for dengue 4
Publication date: Available online 16 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Veronica Elizabeth Mata, Sonia Regina Lambert Passos, Maria Angelica Borges dos Santos, Sibelle Nogueira Buonora, Carlos Augusto Ferreira de Andrade, Monique da Rocha Queiroz Lima, Betina Moreira Costa, Yara Hahr Marques HökerbergAbstractBackgroundAlthough performance of rapid immunochromatographic tests (RITs) for dengue virus (DENV) serotypes 1, 2 and 3 is relatively settled, evidence on accuracy of RITs for DENV-4 are based on studies with small sample sizes and with discrepant results.ObjectivesTo asses...
Source: The Brazilian Journal of Infectious Diseases - January 18, 2020 Category: Infectious Diseases Source Type: research

Influenza A and B in a cohort of outpatient children and adolescent with influenza like-illness during two consecutive influenza seasons
ConclusionsInfluenza A and B are often detected in children and adolescents with ILI episodes, with similar and mild presentation in outpatients. The mismatch between the circulating influenza viruses and the trivalent vaccine offered in Brazil may have contributed to the high frequency of influenza A and B in this population. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - January 15, 2020 Category: Infectious Diseases Source Type: research

Sporadic human cutaneous anthrax outbreak in Shaanxi Province, China: report of two cases from 2018
Publication date: Available online 9 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Yuanyuan Liu, Yongqin Li, Qiaoxia Wang, Jianjun Fu, Fanpu JiAbstractChina’s compulsory annual livestock anthrax vaccination policy has remarkably reduced but not completely eradicated human anthrax infections. Herein we describe a sporadic human cutaneous anthrax outbreak involving two cases in 2018 in Shaanxi Province, both involving herdsman who dealt with unvaccinated and potentially sick cattle. Both patients showed Bacillus anthracis-positive blister smear and blood culture. Treatment with penicillin w...
Source: The Brazilian Journal of Infectious Diseases - January 10, 2020 Category: Infectious Diseases Source Type: research

Septicemia in an immunocompetent adult in the Czech Republic caused by Corynebacterium diphtheriae nontoxigenic strain biotype mitis: emergence of invasive cases in Western Europe
Publication date: Available online 9 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Ricardo Massmann, Jana Zavadilová, Dita Smíšková, Jan Fiksa (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - January 10, 2020 Category: Infectious Diseases Source Type: research

Corrigendum to “Gastrointestinal mucormycosis post lung transplantation” [Braz J Infect Dis 23 (2019) 368–370]
Publication date: Available online 2 January 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Flavio Pola dos Reis, Silvia Vidal Campos, Vera Demarchi Aiello, Maria Irma Seixas Duarte, Marcos Naoyuki Samano, Paulo Manoel Pego-Fernandes (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - January 3, 2020 Category: Infectious Diseases Source Type: research

Proposal of a clinical score to stratify the risk of multidrug-resistant gram-negative rods bacteremia in cancer patients
Publication date: Available online 15 December 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alberto A. Carena, Ana Laborde, Inés Roccia-Rossi, Cynthia J. Palacios, Rosana Jordán, Alejandra Valledor, Andrea Nenna, Patricia Costantini, Miguel Dictar, Fabián Herrera, on behalf of The Argentine Group for the Study of Bacteraemias in Cancer and Stem Cell Transplant (ROCAS) Stem Cell Transplant (ROCAS)AbstractIntroductionMultidrug-resistant gram-negative rods (MDR GNR) represent a growing threat for patients with cancer. Our objective was to determine the characteristics of and risk fac...
Source: The Brazilian Journal of Infectious Diseases - December 21, 2019 Category: Infectious Diseases Source Type: research

Clinical and microbiological characteristics of cryptococcosis at an university hospital in China from 2013 to 2017
ConclusionsMost of the patients with cryptococcosis were not HIV-infected in this study, while patients with HIV had a higher mortality. Reduced susceptibility to fluconazole was observed among C. neoformans isolates, most of them belonged to ST5 genotype VNI having an impact on the effective dose of fluconazole. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 21, 2019 Category: Infectious Diseases Source Type: research

Measles, rubella, mumps and Toxoplasma gondii antibodies in saliva of vaccinated students of schools and universities in São Paulo City, Brazil
DiscussionThe prevalence of antibodies against mumps and rubella after 6–8 years of vaccination was lower than against measles among students. The findings of this study demonstrate the feasibility of saliva sampling for follow-up of vaccine immune status in teenagers. This useful approach allows for IgG detection for vaccine control or epidemiological studies. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 21, 2019 Category: Infectious Diseases Source Type: research

Acknowledgements 2019
Publication date: November–December 2019Source: The Brazilian Journal of Infectious Diseases, Volume 23, Issue 6Author(s): (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - December 19, 2019 Category: Infectious Diseases Source Type: research

Proposal of a clinical score to stratify the risk of multidrug-resistant gram-negative rods bacteraemia in cancer patients
Publication date: Available online 15 December 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alberto A. Carena, Ana Laborde, Inés Roccia-Rossi, Cynthia J. Palacios, Rosana Jordán, Alejandra Valledor, Andrea Nenna, Patricia Costantini, Miguel Dictar, Fabián Herrera, on behalf of The Argentine Group for the Study of Bacteraemias in Cancer, Stem Cell Transplant, (ROCAS)AbstractIntroductionMultidrug-resistant Gram-negative rods (MDR GNR) represent a growing threat for patients with cancer. Our objective was to determine the characteristics of and risk factors for MDR GNR bacteremia in ...
Source: The Brazilian Journal of Infectious Diseases - December 16, 2019 Category: Infectious Diseases Source Type: research

Differential replicative fitness of the four dengue virus serotypes circulating in Colombia in human liver Huh7 cells
This study aimed to compare the replicative fitness of the four dengue virus serotypes and understand the association between the serotypes, their in vitro infection ability, and their replication in target cells. We used three isolates of each DENV serotype to infect Huh-7 cells at an MOI of 0.5. The percentage of infected cells was evaluated by flow cytometry, cell viability was evaluated by MTT assay, and the pathogenicity index was calculated as a ratio of both parameters. The replicative fitness was measured by the number of viral genome copies produced using quantitative PCR and the production of infectious viral pro...
Source: The Brazilian Journal of Infectious Diseases - December 13, 2019 Category: Infectious Diseases Source Type: research

Factors associated to modification of first-line antiretroviral therapy due to adverse events in people living with HIV/AIDS
Publication date: Available online 10 December 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Larissa Negromonte Azevedo, Ricardo Arraes de Alencar Ximenes, Polyana Monteiro, Ulisses Ramos Montarroyos, Demócrito de Barros Miranda-FilhoAbstractAntiretroviral therapy (ART) has modified the outcome of patients with HIV infection, providing virological control and reducing mortality. However, there are several reasons as to why patients may discontinue their antiretroviral therapy, with adverse events being one of the main reasons reported in the literature. This is a case-control nested in a cohort ...
Source: The Brazilian Journal of Infectious Diseases - December 12, 2019 Category: Infectious Diseases Source Type: research

Development and validation of a simple and rapid way to generate low volume of plasma to be used in point-of-care HIV virus load technologies
Publication date: Available online 21 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Isabelle Vasconcellos, Diana Mariani, Marcelo C.V.M. de Azevedo, Orlando C. Ferreira, Amilcar TanuriAbstractA new point-of-care (POC) HIV virus load (VL), mPIMA HIV-1/2 VL, Abbott, USA, has been recently developed. This POC VL requires no skilled person to run and uses a small plasma volume (50 μL). However, obtaining 50 μL of plasma can be a challenge in limited resource settings. We validated a simple and easy method to obtain enough amount of plasma to run a POC VL. The study utilized 149 spe...
Source: The Brazilian Journal of Infectious Diseases - November 22, 2019 Category: Infectious Diseases Source Type: research

Treatment of chronic hepatitis C in patients with chronic kidney disease with Sofosbuvir-basead regimes
ConclusionSofosbuvir-based regimens are effective to treat HCV in patients with CKD. In patients with mild CKD this type of therapy seems to be safe. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 22, 2019 Category: Infectious Diseases Source Type: research

Epitope of dengue virus E protein detect human antibodies associated with mild disease: a potential peptide for vaccine development
Publication date: Available online 21 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Gilma Sánchez-Burgos, Carla Herrera-Nájera, Roberto Cedillo-Rivera, Eric DumonteilAbstractThe antigenic potential of seven immunogenic peptides of the dengue virus was evaluated in the sera of patients with dengue confirmed by IgM/IgG serology. Antibodies IgM and IgG against dengue virus peptides were analyzed by ELISA in 31 dengue sero-positive and 20 sero-negative patients. The P5 peptide showed significant IgG immunoreactivity mostly in the sera of patients with dengue without warning signs in ...
Source: The Brazilian Journal of Infectious Diseases - November 22, 2019 Category: Infectious Diseases Source Type: research

Human herpesvirus 6A active infection in patients with autoimmune Hashimoto's thyroiditis
ConclusionsThe results support a possible role for active HHV-6A infection, demonstrated by the presence of HHV-6 DNA in sera, in the development of HT. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 19, 2019 Category: Infectious Diseases Source Type: research

FilmArray Meningitis/Encephalitis (ME) panel in the diagnosis of bacterial meningitis
Publication date: Available online 16 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Renan Barros Domingues, Márcio Vega dos Santos, Fernando Brunale Vilela de Moura Leite, Carlos SenneAbstractThe precise diagnosis of bacterial meningitis is essential. Cytological and biochemical examination of cerebrospinal fluid (CSF) are not specific. Conventional methods for bacterial meningitis lack sensitivity or take too long for a final result. Therefore, other methods for rapid and accurate diagnosis of central nervous system infections are required. FilmArray meningitis/encephalitis (ME) panel ...
Source: The Brazilian Journal of Infectious Diseases - November 16, 2019 Category: Infectious Diseases Source Type: research

Catheter-related infection due to Papiliotrema laurentii in an oncologic patient: Case report and systematic review
ConclusionP. laurentii infection in humans is usually associated to neoplasia and multiple co-morbidities, and amphotericin B seems to be a reliable agent for treatment. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 16, 2019 Category: Infectious Diseases Source Type: research

A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
Publication date: Available online 16 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Fabianne Carlesse, Liane Esteves Daudt, Adriana Seber, Álvaro Pimenta Dutra, Analy Salles de Azevedo Melo, Belinda Simões, Carla Macedo, Carmem Bonfimi, Eliana Benites, Lauro Gregianin, Marjorie Vieira Batista, Marcelo Abramczyk, Vivian Tostes, Henrique Lederman, Maria Lúcia de Martino Lee, Sandra Logetto, Cláudio Galvão, Arnaldo Lopes ColomboAbstractIn the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infec...
Source: The Brazilian Journal of Infectious Diseases - November 16, 2019 Category: Infectious Diseases Source Type: research

Virus isolation and genotype identification of human respiratory syncytial virus in Guizhou Province, China
Publication date: Available online 14 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Ting Zhao, Zhixu Ye, Binlin Wang, Yuxia Cui, Yingjie Nie, Bin Yang, Kun Chen, Hua Zhang, Hu Fangfang, Yu FuxunAbstractTo investigate the genetic variation and molecular epidemiology characteristics of Human Respiratory Syncytial Virus (HRSV) in Guizhou Province, nasopharyngeal aspirates were collected from patients with acute respiratory infection (ARI) in Guizhou Provincial People's Hospital, from December 2017 to March 2018, and inoculated to Hep-2 cells to isolate HRSV. Cells that showed cytopathic effect (C...
Source: The Brazilian Journal of Infectious Diseases - November 14, 2019 Category: Infectious Diseases Source Type: research

Ghost tablets mimicking intestinal parasite
Publication date: Available online 14 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Lorena Porte, Thomas Weitzel (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 14, 2019 Category: Infectious Diseases Source Type: research

Hepatitis B viremia in HIV-coinfected individuals under antiretroviral therapy
ConclusionsDespite being on ART, a significant proportion of HIV/HBV-coinfected individuals present HBV viremia. Characterization of factors that are associated with this finding may help professionals provide better management to these patients. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 10, 2019 Category: Infectious Diseases Source Type: research

Prevalence and molecular analysis of multidrug-resistant Acinetobacter baumannii in the extra-hospital environment in Mthatha, South Africa
ConclusionExtra-hospital sources such as abattoir and aquatic environments may be a vehicle of spread of MDR A. baumannii strains in the community and hospital settings. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 8, 2019 Category: Infectious Diseases Source Type: research

Infectivity of Simulium damnosum s.l. and therapeutic coverage of ivermectin distribution 10 years post treatment around Owena Dam, Ondo state, Nigeria
ConclusionDespite the years of treatment of onchocerciasis in Owena community, there were still some infective flies capable of transmitting O. volvolus. This could be due to the low rate of therapeutic coverage as a result of non-compliance in the community for various reasons earlier stated. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 5, 2019 Category: Infectious Diseases Source Type: research

Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 AND GST
ConclusionPatients with theCYP2E1 variant genotype or Null GSTT1 showed higher risk of presenting DILI (p = 0.09; OR: 4.57; 95% CI: 0.75–27.6). Individuals with both genotypes had no increased risk compared to individuals with one genotype. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 5, 2019 Category: Infectious Diseases Source Type: research

The effectiveness of the national hepatitis B vaccination program 25 years after its introduction in Iran: a historical cohort study
ConclusionsIran has successfully combined hepatitis B vaccination into regular immunization programs. The WHO goal of reducing HBsAg prevalence to an equivalent of 1% by 2020 has been reached. With respect to vaccination effectiveness and low prevalence of the disease in the country, catch-up hepatitis B vaccination programs for adolescents can guarantee the immunity of the population. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - November 1, 2019 Category: Infectious Diseases Source Type: research

Correlation of interleukin-18 gene polymorphism with the susceptibility of condyloma acuminatum in Chinese population
Publication date: Available online 18 October 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Changyuan Wang, Li Wei, Weilin Chu, Haiyang Yu, Xinjuan Yu, Chunxia LiAbstractHost immunogenetic setting is involved in the regulation of human papillomavirus (HPV) infection and development of condyloma acuminatum (CA). We investigated the correlation of two common single nucleotide polymorphisms (SNPs) (−607C/A and −137G/C) of IL-18 with the susceptibility of CA in a large Chinese cohort. Out of 408 CA patients analyzed, 300 had HPV infection transmitted through sexual contact (SC) and 108 through ...
Source: The Brazilian Journal of Infectious Diseases - October 20, 2019 Category: Infectious Diseases Source Type: research

Ancylostoma duodenale as a cause of upper gastrointestinal bleeding: a case report
Publication date: Available online 14 October 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Andrea Carlin Ronquillo, Lidia Benites Puelles, Luis Pampa Espinoza, Víctor Aguilar Sánchez, José Luis Pinto Valdivia (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - October 15, 2019 Category: Infectious Diseases Source Type: research

Top 10 evidence-based recommendations from the Brazilian Society of Infectious Diseases for the Choosing Wisely Project
Publication date: Available online 25 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alessandro C. Pasqualotto, Camila S. Almeida, Dimas A. Kliemann, Guilherme B. Barcellos, Flávio Queiroz-Telles Filho, Edson Abdala, Mariangela Resende, Filipe P. Batista, José E. Vidal, Jaime Rocha, Sonia M. Raboni, Sergio Cimerman, Ana GalesAbstractThe Choosing Wisely Initiative aims to collect statements from medical societies all over the world on medical interventions that result in no benefit to patients, with the potential to cause harm. In this article we present the views of the Diagnosti...
Source: The Brazilian Journal of Infectious Diseases - September 26, 2019 Category: Infectious Diseases Source Type: research

Unusual oral findings of the toxic epidermal necrolysis in an HIV-infected patient: a case report
Publication date: Available online 25 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Vinicius da Costa Vieira, Viviane Almeida Sarmento, Patricia Miranda Leite Ribeiro, Eduardo Martins Netto, Carlos Brites, Liliane Lins-KustererAbstractErythema multiforme (EM), Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis (TEN) have been reported as possible adverse effects of some classes of first-line antiretroviral drugs (ART) for HIV treatment. Herein we report an unusual presentation of TEN lesions associated with ART in an HIV-infected patient. The patient presented disseminated cutaneous erup...
Source: The Brazilian Journal of Infectious Diseases - September 26, 2019 Category: Infectious Diseases Source Type: research

Influenza in Yucatan in 2018: Chronology, characteristics and outcomes of ambulatory and hospitalized patients
DiscussionOnset of influenza season in Yucatan may reflect a need for rethinking timing of vaccination and of preventive campaigns, as most cases occurred before vaccination period. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - September 25, 2019 Category: Infectious Diseases Source Type: research

Colonization by Pneumocystis jirovecii in patients with chronic obstructive pulmonary disease: association with exacerbations and lung function status
Publication date: Available online 20 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alejandra Cañas-Arboleda, Catalina Hernández-Flórez, Javier Garzón, Claudia Marcela Parra-Giraldo, Juan Felipe Burbano, José Enrique Cita-PardoAbstractExposure to Pneumocystis jirovecii (P. jirovecii) can lead to a wide variety of presenting features ranging from colonization in immunocompetent patients with lung disease, to invasive infections in immunocompromised hosts. Colonization by this fungus in patients with chronic obstructive pulmonary disease (COPD) could be associ...
Source: The Brazilian Journal of Infectious Diseases - September 22, 2019 Category: Infectious Diseases Source Type: research

Prevalence and risk factors for erectile dysfunction in HIV-infected patients in Salvador, Brazil
ConclusionIn a referral center in Salvador city, socio-economic problems were the main factors associated with ED. Psychological impact of poor social conditions should be routinely assessed in patients with ED to implement preventive measures for ED. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - September 22, 2019 Category: Infectious Diseases Source Type: research

Coexistence of low levels of HBsAg and high levels of anti-HBs may increase risk of hepatocellular carcinoma in chronic hepatitis B patients with high HBV load
This study was aimed to assess the association of this serological pattern with hepatocellular carcinoma (HCC) in patients with CHB.MethodsIn this cross-section study, 206 CHB patients with coexistence of HBsAg/anti-HBs and 206 CHB patients with HBsAg alone were included to evaluate the risk of HCC development by logistic regression analysis. In addition, a retrospective cohort of 260 patients with CHB was recruited to estimate the cumulative incidence of HCC by Kaplan–Meier analysis.ResultsThe serological pattern of coexistence of HBsAg/anti-HBs, with high levels of (“High”) HBsAg/low levels of (“L...
Source: The Brazilian Journal of Infectious Diseases - September 20, 2019 Category: Infectious Diseases Source Type: research

Emerging carbapenem-resistant Aeromonas spp. infections in Cali, Colombia
ConclusionEmerging phenotypic carbapenem-resistant infection has been seen in our hospital, most as HAI. High mortality was found, especially in immunocompromised patients and in those who failled empirical treatment with carbapenems. As the main carbapenemases tested were negative, carbapenem-resistant could be attributed to an intrinsic metallo-β-lactamase, CphA encoded by the cphA gene, possible hyperproduction of ampC β-lactamase and/or porins expression. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - September 19, 2019 Category: Infectious Diseases Source Type: research

Design and evaluation of an AFLP molecular marker for the detection of Coccidioides spp. in biological samples
Publication date: Available online 17 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): María del Rocío Reyes-Montes, María Guadalupe Frías-De-León, Isai Victoriano-Pastelín, Gustavo Acosta-Altamirano, Esperanza Duarte-EscalanteAbstractAt present, there is no standardized marker that is routinely used in clinical laboratories to diagnose coccidioidomycosis. Thus, the goals of this study were to obtain a sequence characterized amplified region (SCAR) marker for the identification of Coccidioides spp., evaluate its specificity and sensitivity in fungal DNA-...
Source: The Brazilian Journal of Infectious Diseases - September 19, 2019 Category: Infectious Diseases Source Type: research

Validity and reliability of the 36-Item Short Form Health Survey questionnaire version 2 among people living with HIV in Brazil
Publication date: Available online 3 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Liliane Lins-Kusterer, Juliet Valdelamar, Carolina Villa Nova Aguiar, Marta Silva Menezes, Eduardo Martins Netto, Carlos BritesAbstractBackgroundThe 36-Item Short Form Health Survey questionnaire (SF-36) is a widely used instrument for evaluating health-related quality-of-life (HRQoL). The psychometric validation of the SF-36 version 2.0 (SF-36v2) in HIV-infected patients had not yet conducted in Brazil.AimTo test data quality, reliability and validity of the SF-36v2 as a measure of HRQoL among Brazilian indivi...
Source: The Brazilian Journal of Infectious Diseases - September 5, 2019 Category: Infectious Diseases Source Type: research

HIV-infected youths transitioning from pediatric to adult outpatient care in a teaching tertiary care hospital in São Paulo city, Brazil
This study aimed to (1) describe demographic and clinical characteristics at the first appointment at adult care service following pediatric care of a cohort of Brazilian youths living with HIV since childhood; and (2) retrospectively address adherence and clinical variables in the last two years of pediatric follow-up.MethodsDescriptive study.Results41 consecutive patients referred to adult outpatient care from a pediatric HIV unit were enrolled, median age 19 years, and median lifetime CD4+ nadir 117 cell/mm3; 89% reported previous AIDS-defining conditions. At first laboratory assessment in adult care, only 46% had undetectable (
Source: The Brazilian Journal of Infectious Diseases - September 2, 2019 Category: Infectious Diseases Source Type: research

Gastrointestinal mucormycosis post lung transplantation
Publication date: Available online 30 August 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Flavio Pola dos Reis, Silvia Vidal Campos, Vera Demarchi Aiello, Maria Irma Seixas Duarte, Marcos Naoyuki Samano, Paulo Manoel Pego-Fernandes (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 31, 2019 Category: Infectious Diseases Source Type: research

Evaluation of emerging infectious disease and the importance of SINAN for epidemiological surveillance of Venezuelans immigrants in Brazil
Publication date: Available online 28 August 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Mário Maciel de Lima Junior, Gabbrielle Almeida Rodrigues, Maysa Ruiz de LimaAbstractBackgroundFollowing socio-economic turmoil in Venezuela, millions of the Venezuelan people are migrating to the neighboring Latin American countries including Brazil. Besides the social and economic burden of these migrants, Brazil must manage the health-related issues arising as consequence of these Venezuelan migrants.Poor health services in Venezuela along with unhygienic travelling conditions, lack of food (malnutritio...
Source: The Brazilian Journal of Infectious Diseases - August 30, 2019 Category: Infectious Diseases Source Type: research

Vulnerability to HIV among older men who have sex with men users of dating apps in Brazil
ConclusionsWe highlight some important factors that structure the vulnerability of the MSM surveyed in relation to HIV infection. The findings should be used to customize care for this population, which could bring them in more for health care services. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 30, 2019 Category: Infectious Diseases Source Type: research

Analysis of drug resistance mutations in pulmonary Mycobacterium tuberculosis isolates in the Southern coastal region of Andhra Pradesh, India
ConclusionThe frequency of mutations in MTB in the coastal region of Andhra Pradesh, India, is similar to that in retreatment cases from most settings, with close to 80% in rpoB codon 516, 526, and 531, and over 80% in codons katG 315 and/or inhA promoter. The increase in INH monoresistance underlines the need for greater enforcement of national TB control programs. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - August 15, 2019 Category: Infectious Diseases Source Type: research

Characteristic profile of antibody responses to PPD, ESAT-6, and CFP-10 of Mycobacterium tuberculosis in pulmonary tuberculosis suspected cases in Surabaya, Indonesia
Publication date: Available online 14 August 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Desak Nyoman Surya Suameitria Dewi, Ni Made Mertaniasih, Soedarsono, Yuriko Ozeki, Wayan Tunas Artama, Fihiruddin, Mamiko Niki, Yoshitaka Tateishi, Manabu Ato, Sohkichi MatsumotoAbstractAccurate and rapid diagnostic tools are important aspects of managing tuberculosis (TB) cases appropriately. However, the sensitivity and specificity of diagnostic kits based on immune response such as the tuberculin skin test (TST) and interferon gamma release assay (IGRA) are still debated. Thus, the exploration and assessment o...
Source: The Brazilian Journal of Infectious Diseases - August 15, 2019 Category: Infectious Diseases Source Type: research

Low frequency of hypersensitivity reactions to abacavir in HIV infected patients in a referral center in Bahia, Brazil
Publication date: Available online 31 July 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Raphael Gusmão Barreto, Carlos BritesAbstractAbacavir can cause a multi-systemic hypersensitivity reaction (HSR) in 5–8% of the patients, which is related to HLA-B*57-01 allele. In Brazil, the HLA-B*57-01 screening test became available only in March 2018, several years after abacavir was in use. In this retrospective study we reviewed medical charts of all patients receiving an abacavir-containing regimen to evaluate the frequency of HSR in patients followed at a referral center in Salvador, Brazil. A...
Source: The Brazilian Journal of Infectious Diseases - August 1, 2019 Category: Infectious Diseases Source Type: research

Low tetanus-diphtheria-acellular pertussis (Tdap) vaccine coverage among healthcare workers in a quaternary university hospital in São Paulo, Brazil: need for continuous surveillance and implementation of active strategies
ConclusionsTdap uptake among HCWs was low in our hospital. Providing vaccination at convenient places/times for HCW seems to be the most efficient strategy to increase vaccine uptake. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - July 26, 2019 Category: Infectious Diseases Source Type: research

Rhabdomyolysis following fish consumption: a contained outbreak of Haff Disease in São Paulo
Publication date: Available online 24 July 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Lyna K.R. Almeida, Fernanda Gushken, Dario R. Abregu-Diaz, Roberto Muniz, Luiza H. Degani-Costa (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - July 26, 2019 Category: Infectious Diseases Source Type: research

Hepatitis C prevalence among men who have sex with men in Central Brazil
Publication date: Available online 22 July 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Andreia Alves de Andrade, Ágabo Macêdo da Costa e Silva, Megmar Aparecida dos Santos Carneiro, Sheila Araújo Teles, Regina Maria Bringel MartinsAbstractTo assess the prevalence of hepatitis C virus infection among men who have sex with men (MSM) in Central Brazil, a cross-sectional study was conducted in the City of Goiânia, Central Brazil, using Respondent-Driven Sampling (RDS). All serum samples were tested for anti-HCV and also for alanine aminotransferase (ALT). Anti-HCV positive sampl...
Source: The Brazilian Journal of Infectious Diseases - July 23, 2019 Category: Infectious Diseases Source Type: research

Self-reported syphilis and associated factors among Brazilian young adults: findings from a nationwide survey
Publication date: Available online 22 July 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Natália Luiza Kops, Marina Bessel, Glaucia F. Hohenberger, Adele Benzaken, Eliana WendlandAbstractThe aim of this study was to evaluate self-reported syphilis and associated factors in sexually active young adults (16–25 years old) in the Public Health System in Brazil. This was a cross-sectional study with 8071 participants recruited from 119 primary care units. Of these, 224 (2.86%, 95% CI 2.29–3.43%) reported having the disease. Age, lower socio-economic class, being a smoker, not using a cond...
Source: The Brazilian Journal of Infectious Diseases - July 23, 2019 Category: Infectious Diseases Source Type: research