Triple antithrombotic therapy versus double antiplatelet therapy after percutaneous coronary intervention with stent implantation in patients requiring chronic oral anticoagulation: a meta-analysis.

CONCLUSIONS: Triple therapy is more efficacious in reducing the occurrence of ischemic stroke in PCI-s patients with an indication of chronic oral anticoagulation (OAC), compared with DAPT. However, it significantly increased major and minor risk of bleeding. It is imperative that further prospective randomized controlled trials are required to defne the best therapeutic strategy for patients with an indication of chronic OAC undergoing PCI-s. PMID: 23823830 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23823830?dopt=Abstract

Source: Chinese Medical Journal - July 1, 2013 Category: Journals (General) Authors: Saheb KJ, Deng BQ, Hu QS, Xie SL, Geng DF, Nie RQ Tags: Chin Med J (Engl) Source Type: research