Sertraline Reduces Albuminuria by Interfering with Caveolae-Mediated Endocytosis through Glomerular Endothelial and Epithelial Cells.

CONCLUSIONS: Ser interfered with albumin internalization through the caveolae into GEnCs and podocytes and reduced albuminuria. Dynamin inhibitors may serve as a novel therapeutic option for reducing albuminuria in glomerulonephritis.
PMID: 31655808 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - October 24, 2019 Category: Urology & Nephrology Authors: Moriyama T, Karasawa K, Hasegawa F, Uchida K, Nitta K Tags: Am J Nephrol Source Type: research